Dr. Vikash Kumar Dubey
Prof. Vikash Kumar Dubey is Professor (HAG) at School of Biochemical Engineering, IIT (BHU), Varanasi and Currently Dean (Research & Development), IIT (BHU) Varanasi. Before joining IIT (BHU) Varanasi in May 2018, he was Professor (January 2014 to May 2018) at IIT Guwahati where he has also served as Assistant Professor/Associate Professor (September 2006 onward). He was postdoctoral fellow at Florida State University, USA (January 2004 to September 2006) before joining IIT Guwahati. He is currently Coordinator/Head, School of Biochemical Engineering (Feb. 2020 onward) and taking care of overall administration of the school. He was also Associate Dean (Academic Affairs), IIT-BHU (June 2019 - Feb 2022) and was looking after undergraduate academic affairs. He had several other administrative experiences at IIT Guwahati at various levels including Head, Chairman (Student Welfare Board), Faculty-in-Charge etc. He is also a member of various national level committees, expert committees, faculty selection committee etc. He has published over 166 articles in peer reviewed Journal(s) and over 85 conference presentations/proceedings/invited talks. He has seven awarded and licensed USA patents as well as three published Indian patents to his credit. He has also written several book chapters and one NPTEL online course (40 lectures). His scientific contributions are recognised by several awards including Best Teacher Award-2021 of IIT (BHU) Varanasi, fellowship/membership of national/international scientific societies/ academies, Editorship of several journals etc. He has guided twenty-one PhD students (21 awarded), twenty-four MTech students (24 awarded including final year IDD thesis), several postdoctoral fellows, project fellows, trainees etc.
Professional Experience
--July 2020- till date : Professor (HAG) School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi.
--January 2014 onward: Professor
- May 2018- till date : Professor, School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi.
- January 2014- May 2018: Professor, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati.
-December 2009- January 2014: Associate Professor, Department of Biotechnology, Indian Institute of Technology Guwahati.
-September 2006- November 2009: Assistant Professor, Department of Biotechnology, Indian Institute of Technology Guwahati.
-January 2004- September 2006: Post-Doctoral Research Associate, Florida State University, Tallahassee, Florida, USA.
-September 2002-January 2003: Fellow of Intituto Pasteur-Foundazione Cenci Biolognetti, Rome, Italy.
-Senior Research Fellowship, CSIR, Government of India
-Training Fellowship from Intituto Pasteur-Foundazione Cenci Biolognetti, Rome, Italy.
-Junior Research Fellowship, CSIR, Government of India.
-Qualified national eligibility test (CSIR-NET), for research fellowship and eligibility for lectureship.
Membership of Scientific Society
-Fellow, Royal Society of Biology, United Kingdom
- Fellow: National Academy of Biological sciences
-Fellow: Biotechnology Research Society of India
-Fellow: Association of Biotechnology and Pharmacy
-The National Academy of Sciences, India: Life member. ( MNASc)
- Fellow: Society of Applied Biotechnology
- Member, International Society of Infectious Diseases
-Bioinformatics and Drug Discovery Society : Life member.
- Society of Biological Chemist (India): Life member.
-Biotechnology Research Society of India: Life member.
- Leishmaniasis Research Society (India): Life member.
-Association of Biotechnology and Pharmacy: Life member.
- Indian Science Congress Association : Life member.
- National academy of Biological sciences: Life member.
- Best Teacher Award-2021 of IIT (BHU) Varanasi.
- Member, Board of Governors (April 2017-April 2019 ), The Biotech Research Society of India (BRSI).
- Elected as FRSB (Fellow, Royal Society of Biology, United Kingdom ) : 1-Jan. 2018 onward
- Vice President , Bioinformatics and Drug Discovery Society [BIDDS] (July 2017 onward)
- Prize for Biomedical Research Conducted in Underdeveloped areas–2016 by Indian Council for Medical Research, Government of India
- Dr. P.N. Raju Oration Award-2012 by Indian Council for Medical Research, Government of India
- Elected as FBRS (Fellow, Biotech Research Society) of India in recognition of outstanding research contributions to Medical Biotechnology (2014)
- Elected as FABP (Fellow, Association of Biotechnology and Pharmacy ) in recognition of outstanding research contributions to Medical Biotechnology (2014)
- Prof. Umakant Sinha Memorial Award of the Indian Science Congress Association (ISCA) for the year 2013-2014
- B.M. Birla Science Prize in Biology for Year 2012
- Malviya Memorial Award (Young Faculty) for 2011 by Biotech Research Society of India (Nov., 2012).
- Elected as Fellow of National Academy of Biological Sciences (July, 2013).
- Extended Innovative Young Biotechnologist Award by DBT. Government of India (July 2013) [Cash prize Rs. 2 Lakhs for 2 more years with additional project funding].
- Innovative Young Biotechnologist Award for 2009 (IYBA-2009) by DBT. Government of India February 2010 [Gold medal,Citation,Cash prize Rs. 3 Lakhs for 3 years period along with a major project funding].
- Young Scientist Award for 2009 by Biotech Research Society of India [The award consists of a citation and medal].
- Young Scientist Award (2009-10) by National Academy of Agriculture Sciences [Citation, a gold plated silver medal and cash prize of Rs. 25,000]
- Young Scientist Award for 2009-10 by Indian Society of Chemists and Biologists (ISCB) [The award consists of a citation, medal and cash prize].
- Young Scientist Award for 2011 by Society of Applied Biotechnology, Award ceremony was held at Kolhapur, Maharashtra, Feb. 24, 2012.
- Awarded "Bharat Joyoti Award" for meritorious services and outstanding performance by India International Friendship Society (2012).
- Associate Fellow: National Academy of Agriculture Sciences, India.
- Elected as MNASc (Member, The National Academy of Sciences, India). April 2010.
Student Awards (under my supervision)
- PhD work of Mr. Gundappa Saha has been awarded Prime minister doctoral Fellowship. It is a unique, highest-paying scholarship of Science & Engineering Research Board, Department of Science and Technology, Government of India and Confederation of Indian Industry. He is working on Leishmania project in collaboration with Cadila Pharmaceuticals Limited.
- Prakash Saudagar and Vikash Kumar Dubey. "Betulin attached to functionalized carbon nanotubes showed better efficacy against Leishmania parasite". 2nd International Conference on Infectious Diseases and Nanomedicine-2015 (ICIDN-2015), Kathmandu, Nepal,December 15-18, 2015. [ Best poster Award ].
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Mr. Ritesh Kumar , PhD student with Dr. V.K. Dubey, received Best poster Award at International Conference on "Future Prospects of Advancements in Biological Sciences, Health Issues & Environmental Protection; on 07 - 08 Feb, 2014 at Indira Gandhi Pratishthan, Lucknow
- Ms. Mousumi Das, PhD student with Dr. V.K. Dubey, received Best Oral Presentation Award during International Conference on Health, Environment and Industrial Biotechnology BioSangam -2013. Allahabad, November 21 - 23, 2013
- Mr. Prakash Saudagar, PhD student with Dr. V.K. Dubey, received Best poster Award during 80th Annual Meeting of Society of Biological Chemists, India held at Lucknow, November 12-15, 2011.
- Mr. Anil Kumar Shukla, Ph.D student withr Dr. V.K. Dubey, has been awarded travel award by Department of Science and Technology for attending European Molecular Biology Organization (EMBO) meeting 2011 held at Vienna.
- Ms. Nandini Sarkar, PhD student with Dr. V.K. Dubey, awarded International Union of Biochemistry and Molecular Biology (IUBMB) full travel fellowship to attend 21st IUBMB and 12th Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) International Congress of Biochemistry and Molecular Biology held during 2-7 August 2009 in Shanghai, China.
- Ms. Nandini Sarkar, PhD student with Dr. V.K. Dubey, received Young Scientist Program Award : 21st International Union of Biochemistry and Molecular Biology (IUBMB) and 12th Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) International Congress of Biochemistry and Molecular Biology held during 2-7 August 2009 in Shanghai, China.
- Ms. Nandini Sarkar, PhD student with Dr. V.K. Dubey, received B.S Narasinga Rao Best poster Award during 77th Annual Meeting of Society of Biological Chemists, India held at IIT Madras, Chennai December 18-20, 2008
- Any Other Relevant Information
- Associate Editor: Scientific Report Nature Publishing Group: July 2015
- Associate Editor: Journal of Proteins and Proteomics : Dec. 2008 onward [ Publisher: Springer]
- Editorial Board Member: Protein and Peptide Letters [Bentham Science Journal; Impact factor 1.99) : Jan. 2014 onward
- Associate Editor : BMC Biotechnology (Impact factor 2.59) : July 2014 -July 2017
- Editorial Board member: Dataset Papers in Biology [Biotechnology section and Biophysics section]: 2013-2014
- Editorial Board member: ISRN Structural Biology (Hindawi Journal): 2013 onward
- Editorial Board member: Cloning & Transgenesis (Omics Group Journal): 2013 onward
- Editorial Advisory board: Advances in Natural and Applied Sciences.
- Editor: Biotechnology and Molecular Biology Reviews : Dec. 2008 onward
- Editorial Advisory board: International Journal of Medical Sciences and Technology.
- Editorial Advisory board: International Journal of Life Sciences and Technology.
- Editorial Advisory board: International Journal of BioSciences, Healthcare Technology and Management (IJBHTM).
- Editor board member of International Journal of BioSciences and Technology; International Journal of Biological Sciences and Technology; International Journal of BioSciences, Psychiatry and Technology ; International Journal of Innovation; International Journal of BioSciences, Agriculture and Technology.
- Editorial Review Board member of Scientific Journals International (SJI).
- Reviewer for several journals like Biochemistry (ACS), Phytochemistry, International Journal of Biological Macromolecules, Biotechnology, Medicinal Chemistry (ACS), Process Biochemistry, Parasitology International, Experimental parasitology, Parasitology Research, Acta Tropica, PLOS journals, and Molecular Biology Reviews etc.
- https://publons.com/author/1000683/prof-vikash-kumar-dubey#profile)
- Senior Research Fellowship, CSIR, Government of India.
- Training Fellowship from Intituto Pasteur-Foundazione Cenci Biolognetti, Rome, Italy.
- Junior Research Fellowship, CSIR, Government of India.
- Qualified national eligibility test (CSIR-NET), for research fellowship and eligibility for lectureship.
167. Manas Sarma, Kushal Bora, Preeti Ranjan, Vikash Kumar Dubey* (2024) Identification of novel anti-leishmanials targeting glutathione synthetase of the parasite: a drug repurposing approach, FEBS Letters, https://doi.org/10.1002/1873-3468.15016 [*Corresponding author; Publisher: Wiley].
166. Kushal Bora, Manash Sarma, Shankar Prasad Kanaujia, Vikash Kumar Dubey* (2024) . Development of novel dual-target drugs against visceral leishmaniasis and combinational study with miltefosine, Free Radical Biology and Medicine, 225, 275-285, https://doi.org/10.1016/j.freeradbiomed.2024.10.257. [*Corresponding author; Publisher: Elsevier].
165. Preeti Ranjan, Manash Sarma, Vikash Kumar Dubey* (2024) Biochemical and biophysical characterization of Leishmania donovani citrate synthase, International Journal of Biological Macromolecules, 279, Part 3, 135400, [*Corresponding author; Publisher: Elsevier].
164. Baishakhi Mahapatra, Abhishek Singh, Arpita Banerjee, Shruti Sirohi, Samer Singh, Vikash K. Dubey, Rakesh K. Singh (2024) A squalene oil emulsified MPL-A and anti-CD200/CD300a antibodies adjuvanted whole-killed Leishmania vaccine provides durable immunity against L. donovani parasites, Vaccine, 42 (26), 126373 https://doi.org/10.1016/j.vaccine.2024.12637 (Publisher: Elsevier].
163. Abhishek Singh, Baishakhi Mahapatra, Arpita Banerjee, Samer Singh, Sangram Singh, Vikash K Dubey, Pradeep Das, Rakesh K Singh (2024). Leishmania antigens activated CD4+ T cells expressing CD200R receptors are the prime IL-10 producing phenotype and an important determinant of visceral leishmaniasis pathogenesis . Cytokine, 173, 156435 [Publisher: Elsevier].
162. Borkotoky Subhomoi, Prakash Archisha, Modi Prakash Gyan and Vikash KumarDubey * (2024) Computational Repurposing of Potential Dimerization Inhibitors against SARS-CoV-2 Main Protease, Letters in Drug Design & Discovery 21(4), 799 - 808 . https://dx.doi.org/10.2174/1570180820666230111141203 [*Corresponding author; Publisher: Bentham ].
161. Kushal Bora, Manash Sarma, Shankar Prasad Kanaujia, Vikash Kumar Dubey* (2023). Dual-target drugs against Leishmania donovani for potential novel therapeutics. Scientific Reports 13, 18363 [*Corresponding author; Publisher: Nature ].
160. Preeti Ranjan and Vikash Kumar Dubey*(2023). Novel chemical scaffold as potential drug against Leishmania donovani: Integrated computational and experimental approaches. Journal of Cellular Biochemistry, 124(9), 1404-1422 https://doi.org/10.1002/jcb.30455 [*Corresponding author; Publisher: Wiley].
159. Preeti Ranjan and Vikash Kumar Dubey*(2023). Identification of Potential Anti-leishmanial Compounds from Natural Sources against Citrate Synthase enzyme using structure-based drug designing. Journal of Molecular Structure, 1295 (Part 2), 136556 https://doi.org/10.1016/j.molstruc.2023.136556 [*Corresponding author; Publisher: Elsevier].
158. Gourav Singh, Jobin Thomas, Sahil Wadhawa, Anurag Kashyap, Syed Ajijur Rahaman, Subhomoi Borkotoky, Agnisha Datta, Gireesh Kumar Singh, Indubhusan Mishra, Geeta Rai, Jitendra Satija, Vikash Kumar Dubey, Gyan Modi. (2023) Repurposing the in-house generated Alzheimer’s disease targeting molecules through computational and preliminary in-vitro studies for the management of SARS-Coronavirus-2. Molecular Diversity, doi: 10.1007/s11030-023-10717-4.[Publisher: Springe]
157. Manash Sarma, Subhomoi Borkotoky and Vikash Kumar Dubey*(2023). Structure-based drug designing against Leishmania donovani using docking and molecular dynamics simulation studies: exploring glutathione synthetase as a drug target. Journal of Biomolecular Structure and Dynamics, https://doi.org/10.1080/07391102.2023.2240429 [*Corresponding author; Publisher: Taylor and Francis].
156. Naveena Menpadi, Jay Prakash, Debanjan Kundu, Pranjal Chandra and Vikash Kumar Dubey*(2023). Integrated computational and experimental approach for novel anti-leishmanial molecules by targeting Dephospho-coenzyme A kinase. International Journal of Biological Macromolecules, 232, 31, 123441 [*Corresponding author; Publisher: Elsevier].
155. Preeti Ranjan and Vikash Kumar Dubey* (2023) Krebs cycle enzymes for targeted therapeutics and immunotherapy for anti-leishmanial drug development using: Pathways, potential targets, and future perspectives Life Sciences, https://doi.org/10.1016/j.lfs.2022.121314 [*Corresponding author; Publisher: Elsevier].
154. Rahul Kumar, Vinish Ranjan Srivastava, Supratim Mahapatra, Daphika S Dkhar, Rohini Kumari, Kumari Prerna, Vikash Kumar Dubey, Pranjal Chandra. (2023) Drug encapsulated lipid-polymeric nanohybrid as a chemo-therapeutic platform of cancer. Nanotheranostics. 7(2):167–175. doi: 10.7150/ntno.81173
153. Tanuj Handa DebanjanKundu and Vikash Kumar Dubey* (2022) Perspectives on Evolutionary and Functional importance of Intrinsically Disordered Proteins.International Journal of Biological Macromolecules https://doi.org/10.1016/j.ijbiomac.2022.10.120 [*Corresponding author; Publisher: Elsevier].
152. Kumari Prerna and Vikash Kumar Dubey* (2022) Beclin1-mediated interplay between autophagy and apoptosis: New understanding. International Journal of Biological Macromolecules. 204, 15 258-273. [*Corresponding author; Publisher: Elsevier].
151. Archisa Prakash, Subhomoi Borkotoky, Vikash Kumar Dubey* (2022) Targeting two potential sites of SARS-CoV-2 main protease through computational drug repurposing. Journal of Biomolecular Structure and Dynamics, 1-11 doi: https://doi.org/10.1080/07391102.2022.2044907. [*Corresponding author; Publisher: Taylor and Francis].
150. Manish Kumar Gupta, Adarsh Kumar Chiranjivi, Tanmay Dutta, Vikash Kumar Dubey & Latha Rangan. (2022) Synthesis and characterization of zinc derivatized 3, 5-dihydroxy 4′, 7-dimethoxyflavone and its anti leishmaniasis activity against Leishmania donovani. BioMetals , 35, 285–30 [ Publisher: Springer].
149. Rahul Kumar, Supratim Mahapatra, Vikash Kumar Dubey, Pranjal Chandra. (2022) N-acetyl-d-glucosamine decorated nano-lipid-based carriers as theranostics module for targeted anti-cancer drug delivery. Materials Chemistry and Physics 282, 125956. [Publisher: Elsevier].
148. Rahul Kumar, Daphika S.Dkhar, Rohini Kumari, Divya, Supratim Mahapatra, Vikash Kumar Dubey, and Pranjal Chandra (2022). Lipid based nanocarriers: Production techniques, concepts, and commercialization aspect. Journal of Drug Delivery Science and Technology https://doi.org/10.1016/j.jddst.2022.103526
147. R Kumar, N Varshney, S Mahapatra, SK Mahto, VK Dubey, P Chandra (2022). Design and development of lactoferrin conjugated lipid polymer nanobiohybrid for cancer theranostics. Materials Today Communications 31 103548 https://doi.org/10.1016/j.mtcomm.2022.103548
146. Rahul Kumar, Daphika S Dkhar, Rohini Kumari, Supratim Mahapatra, Ananya Srivastava, Vikash Kumar Dubey and Pranjal Chandra (2022). Ligand conjugated lipid-based nanocarriers for cancer theranostics. Biotechnology and Bioengineering 119 (11), 3022-3043. https://doi.org/10.1002/bit.28205
145. SunitaYadav, Jay Prakash, Om PrakashSingh, Mallikarjuna Rao Gedda, Shashi Bhushan Chauhan, Shyam Sundar and Vikash Kumar Dubey* (2021) IFN-γ+ CD4+T cell- Driven prophylactic potential of recombinant LDBPK_252400 hypothetical protein of Leishmania donovani against Visceral Leishmaniasis. Cellular Immunology; doi 10.1016/j.cellimm.2020.104272 [*Corresponding author; Publisher: Elsevier].
144. Debanjan Kundu and Vikash Kumar Dubey* (2021) Potential alternatives to current cholinesterase inhibitors: An in silico drug repurposing approach. Drug Development and Industrial Pharmacy; https://doi.org/10.1080/03639045.2021.1952216 [*Corresponding author; Publisher: Taylor and Francis].
143. Manish Kumar Gupta, Sanjana Senthil kumara, Adarsh Kumar Chiranjivi, Kishore Banik, SosmithaGirisa, Ajaikumar Bahulayan Kunnumakkara, Vikash Kumar Dubey, LathaRangan (2021) Antioxidant, anti-tyrosinase and anti-inflammatory activities of 3,5-dihydroxy-4′,7-dimethoxyflavone isolated from the leaves of Alpinia nigra. Phytomedicine Plus, 1(3), 100097
142. Subhomoi Borkotoky, Manidipa Banerjee, Gyan Prakash Modi, VikashKumar Dubey*. (2021) Identification of high affinity and low molecular alternatives of boceprevir against SARS-CoV-2 main protease: a virtual screening approach. Chemical Physics Letters https://doi.org/10.1016/j.cplett.2021.138446 [*Corresponding author; Publisher: Elsevier].
141. Kumari Prerna and Vikash Kumar Dubey* (2021) Repurposing of FDA-approved drugs as Autophagy Inhibitors in tumor Cells Journal of Biomolecular Structure and Dynamics, https://doi.org/10.1080/07391102.2021.1873862 . [*Corresponding author; Publisher: Taylor and Francis].
140. Umesh#, Kumari Prerna# and Vikash Kumar Dubey* (2021) Virtual screening and repurposing of FDA-approved drugs from ZINC Database to identify potential autophagy inhibitors exploiting Autophagy Related4A Cysteine Peptidaseas a target: potential as novel anti-cancer molecule. Journal of Biomolecular Structure and Dynamics, https://doi.org/10.1080/07391102.2020.1869100 . [# Equal Contribution; *Corresponding author; Publisher: Taylor and Francis].
139. Himanshu Rai, Atanu Barik, Yash Pal Singh, Akhil Suresh, Lovejit Singh, Gourav Singh, Usha Yogendra Nayak, Vikash Kumar Dubey, Gyan Modi. (2021) Molecular docking, binding mode analysis, molecular dynamics, and prediction of ADMET/Toxicity properties of selective potential antiviral agents against SARS-CoV-2 main protease: An effort towards drug repurposing to combat COVID-19. Molecular Diversity, 25,1905-1927. doi: 10.1007/s11030-021-10188-5 [Publisher: springer]
138. Ribhav Mishra, Vibhuti Joshi, Arun Upadhyay, Ayeman Amanullah, Ankur Rakesh Dubey, Sarika Singh, Vikash Kumar Dubey, Krishna Mohan Poluri, Nihar Ranjan Jana, Amit Mishra (2021). LRSAM1 E3 ubiquitin ligase promotes proteasomal clearance of E6-AP protein, Cellular Signalling, 77, 2021, 109836, https://doi.org/10.1016/j.cellsig.2020.109836. [Publisher: Elsevier].
137. Gundappa Saha, Adarsh Kumar Chiranjivi, Bakulesh M Khamar, Kumari Prerna, Manish Kumar and Vikash Kumar Dubey* (2020). BLIMP-1 mediated downregulation of TAK1 and p53 molecules is crucial in the pathogenesis of kala-azar. Frontiers in Cellular and Infection Microbiology,10, 655 doi: 10.3389/fcimb.2020.594431 [*Corresponding Author)
136. Sunita Yadav, Jay Prakash, Harish Shukla, Kanhu Charan Das, Timir Tripathi and Vikash Kumar Dubey* (2020). Design of a multi-epitope subunit vaccine for immune-protection against Leishmania parasite . Pathogens and Global Health. DOI: 10.1080/20477724.2020.1842976, https://doi.org/10.1080/20477724.2020.1842976 .[*Corresponding Author; Publisher: Taylor & Francis)
135. Debanjan Kundu and Vikash Kumar Dubey*. (2021) Purines and Pyrimidines: Metabolism, Function and Potential as therapeutic options in neurodegenerative diseases. Current Protein & Peptide Science . 2021, 22 (2),170-189 [*Corresponding Author;)
134. Adarsh Kumar Chiranjivi, Jay Prakash, Gundappa Saha, Pranjal Chandra and Vikash Kumar Dubey* (2020) Mutational studies on Leishmania donovani dihydrolipoamide dehydrogenase (LdBPK291950.1) indicates that the enzyme may not be Classical class-I pyridine nucleotide-disulfide oxidoreductase. Int J Biol Macromol. 164, 2141-2150 [*Corresponding author; Publisher: Elsevier].
133. Umesh,. Kundu, D., Selvaraj, C., Singh, S.K. & Dubey, V.K.* (2020). Identification of new anti- nCoV drug chemical compounds from Indian spices exploiting SARS- CoV-2 main protease as target. Journal of Biomolecular Structure and Dynamics, May 2:1-9 https://doi.org/10.1080/
132. Chandrabose Selvaraj, Umesh Panwar, Dhurvas Chandrasekaran Dinesh, Evzen Boura, Poonam Singh, Vikash Kumar Dubey, Sanjeev Kumar Singh (2020) Manuscript title: Microsecond MD Simulation and Multiple-Confirmation Virtual Screening to Identify Potential Anti-COVID-19 Inhibitors Against SARS-CoV-2 Main Protease. Frontiers in Chemistry doi: 10.3389/fchem.2020.595273
131. Raj, S., Sasidharan, S., Balaji, S.N., Dubey, V. K., & Saudagar, P. (2020). Review on Natural Products as an alternative to contemporary anti-leishmanial therapeutics. Journal of Proteins and Proteomics, 11, 135–158. [Publisher: springer]
130. Santanu Sasidharan, Chandrabose Selvaraj, Sanjeev Kumar Singh, Vikash Kumar Dubey, Sachin Kumar, Arsenio M. Fialho & Prakash Saudagar. (2020) Bacterial protein azurin and derived peptides as potential anti-SARS-CoV-2 agents: insights from molecular docking and molecular dynamics simulations. Journal of Biomolecular Structure and Dynamics. https://doi.org/10.1080/07391102.2020.1787864
129. Debanjan Kundu, Kumari Prerna, Chaurasia, R., Bharty, M. K., and Vikash Kumar Dubey* (2020). Advances in protein misfolding, amyloidosis and its correlation with human diseases. 3 Biotech. 10(5):193. https://doi.org/10.1007/
128. Debanjan Kundu, Umesh, and Vikash Kumar Dubey* (2020). Interaction of selected biomolecules and metabolites with amyloidogenic proteins, Journal of Biomolecular Structure and Dynamics, DOI: 10.1080/07391102.2020.1760138. [*Corresponding author; Publisher: Taylor & Francis].
127. Gianni Colotti, Roberto Di Santo, Marina Gramiccia, Trentina Di Muccio, Jay Prakash, Sunita Yadav, Vikash Kumar Dubey, Theo Battista, Aasia Bibi and Andrea Ilari. (2020) Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism.Amino acid, 52(2):247-259 doi: 10.1007/s00726-019-02731-4 [Publisher: Springer]
126. Soumi Das, Kamalesh Verma, Vikash K.Dubey, Lal Mohan Kundu (2020) Fabrication of nanoparticles from a synthesized peptide amphiphile as a versatile therapeutic cargo for high antiproliferative activity in tumor cells. Bioorg Chem. 2020 Jan;94:103440. doi: 10.1016/j.bioorg.2019.103440.
125. Gundappa Saha, Bakulesh Khamar, Kumari Prerna, Manish Kumar and Vikash Kumar Dubey* (2019) BLIMP-1 plays important role in the regulation of macrophage pyroptosis for the growth and multiplication of Leishmania donovani. ACS Infectious Diseases, 2019, 9(1):16209 doi: 10.1021/acsinfecdis.9b00186. [*Corresponding author; Publisher: American Chemical Society].
124. Shweta Raj, Gundappa Saha, Santanu Sasidharan, Vikash Kumar Dubey, Prakash Saudagar (2019) Biochemical characterization and chemical validation of Leishmania MAP Kinase-3 as a potential drug target . Scientific Reports, 2019, 9(1):16209 [ Publisher: Nature Publishing Group]
123. Kamalesh Verma , Debanjan Kundu , Lal Mohan Kundu , Ashish Kumar Singh , Vikash Kumar Dubey* (2019) Folding and stability of recombinant azoreductase enzyme from Chromobacterium violaceum. Enzyme and Microbial Technology. 2019, 131,109433. [*Corresponding author; Publisher: Elsevier].
122. Shweta Raj ,Santanu Sasidharan ,Vikash Kumar Dubey, Prakash Saudagar (2019) Identification of lead molecules against potential drug target protein MAPK4 from L. donovani: An in-silico approach using docking, molecular dynamics and binding free energy calculation. PLoS One. 2019 Aug 19;14(8):e0221331. doi: 10.1371/journal.pone.0221331. eCollection 2019.
121. Prakash J, Yadav S, Saha G, Chiranjivi AK, Kumar S, Sasidharan S, Saudagar P, Dubey VK* (2019) Episomal expression of human glutathione reductase (HuGR) in Leishmania sheds light on evolutionary pressure for unique redox metabolism pathway: Impaired stress tolerance ability of Leishmania donovani. Int J Biol Macromol. 2019 Jan;121:498-507. [*Corresponding author; Publisher: Elsevier].
120. Shyamali Sarma, DavidOrtega, Nigel P.Minton,Vikash Kumar Dubey,Vijayanand S.Moholkar (2019) Homologous overexpression of hydrogenase and glycerol dehydrogenase in Clostridium pasteurianum to enhance hydrogen production from crude glycerol, Bioresource Technology, 2019, 284, 168-177 [Publisher: Elsevier].
119. Verma K, Saha G, Kundu LM, Dubey VK* (2019) Biochemical characterization of a stable azoreductase enzyme from Chromobacterium violaceum: Application in industrial effluent dye degradation. Int J Biol Macromol. 2019, 121:1011-1018. [*Corresponding author; Publisher: Elsevier].
118. Barman J, Kumar R, Saha G, Tiwari K, Dubey VK* (2018) Apoptosis: Mediator Molecules, Interplay with Other Cell Death Processes and Therapeutic Potentials. Curr Pharm Biotechnol. 2018;19(8):644-663.[*Corresponding author; Publisher: Bentham].
117. Saha G, Khamar BM, Singh OP, Sundar S, Dubey VK* (2018) Leishmania donovani evades Caspase 1 dependent host defense mechanism during infection. Int J Biol Macromol. 2018 22;126:392-401[*Corresponding author; Publisher: Elsevier]. Media covereage of the article: https://www.natureasia.com/en/nindia/article/10.1038/nindia.2019.1
116. Najar IN, Sherpa MT, Das S, Verma K, Dubey VK, Thakur N (2018) Geobacillus yumthangensis sp. nov., a thermophilic bacterium isolated from a north-east Indian hot spring. Int J Syst Evol Microbiol. 2018 68(11):3430-3434.
115. Anupriya Baranwal, Adarsh Kumar Chiranjivi, Ashutosh Kumar, Vikash Kumar Dubey* , and Pranjal Chandra* (2018) Design of commercially comparable nanotherapeutic agent against human disease-causing parasite, Leishmania. Scientific Reports, 2018, 8(1):8814 [ *Joint Corresponding author; Publisher: Nature Publishing Group]
114. Kartikeya Tiwari and Vikash Kumar Dubey* (2018) Leishmania donovani asparaginase variants exhibit cytosolic localization. . International Journal of Biological Macromol. 2018, 114, 35-39 [*Corresponding author; Publisher: Elsevier].
113. Adarsh Chiranjivi and Vikash Kumar Dubey* (2018) Dihydrolipoamide dehydrogenase from Leishmania donovani: New insights through biochemical characterization. International Journal of Biological Macromol. 2018, 112:1241-124. [*Corresponding author; Publisher: Elsevier].
112. Prachi Bhalla, Sabera Sultana, Adarsh Chiranjivi, Anil Saikia and Vikash Kumar Dubey* (2018) synthesis of Methyl 4-(7-hydroxy-4,4,8-trimethyl-3-oxabicyclo[3.3.1]nonan-2-yl)benzoate and their evaluation as anti-leishmanial: Synergistic effect with Miltefosine. Antimicrobial Agents and Chemotherapy, 2018, 62(2):e01810-17 doi: 10.1128/AAC.01810-17. [Epub ahead of print] . [*Corresponding author; Publisher: American Society of Microbiology].
111. Kartikeya Tiwari and Vikash Kumar Dubey.* (2018) Fresh insights into the pyrimidine metabolism in the trypanosomatids. Parasites & Vectors 2018, 11(1):87. doi: 10.1186/s13071-018-2660-8[*Corresponding author; Publisher: BioMed Central].
110. Vidhya V. M., Vikash Kumar Dubey and Karthe Ponnuraj. Identification of two natural compound inhibitors of Leishmania donovani Spermidine Synthase (SpdS) through molecular docking and dynamic studies. J Biomol Struct Dyn. 2017 Sep 5:1-16. doi: 10.1080/07391102.2017.1366947. [Publisher: Taylor and Francis].
109. Shalini Singh, Ekta Kumari, Ruchika Bhardwaj, Ritesh Kumar and Vikash Kumar Dubey*. Molecular events leading to death of Leishmania donovani under spermidine starvation after hypericin treatment. Chemical Biology & Drug Design, 2017, 90, 962-971 [*Corresponding author; Publisher: Wiley] Media coverage
108. Ritesh Kumar, Kartikeya Tiwari and Vikash Kumar Dubey*. Methionine aminopeptidase 2 is a key regulator of apoptotic like cell death in Leishmania donovan, Scientific Reports, 2017, 7: 95. [*Corresponding author;Publisher: Nature Publishing Group]. Research Highlight of the article published in Nature India.
107. Ruchika Bhardwaj , Mousumi Das , Shalini Singh, Adarsh Kumar Chiranjivi, Sitraraau Vijaya Prabhu , Sanjeev Kumar Singh and Vikash Kumar Dubey * Evaluation of CAAX prenyl protease II of Leishmania donovani as potential drug target: infectivity and growth of the parasite is significantly lowered after the gene knockout. European Journal of Pharmaceutical Sciences , 2017, 102,156-160 [*Corresponding author; Publisher: Elsevier].
106. Shyamali Sarma, Avinash Anand, Vikash Kumar Dubey, V.S. Moholkar. Metabolic flux network analysis of hydrogen production from crude glycerol by Clostridium pasteurianum. Bioresource Technology, 2017, S0960-8524(17)30450-9 [ Publisher: Elsevier].
105. Sitrarasu Vijaya Prabhu, Kartikeya Tiwari, Venkatesan Suryanarayanan, Vikash Kumar Dubey* and Sanjeev Kumar Singh*. Exploration of potent molecules against CAAX prenyl protease I of Leishmania donovani through Pharmacophore based virtual screening approach. Combinatorial Chemistry & High Throughput Screening, 2017, 20, 255-271 [*Joint corresponding authors; Publisher: Bentham Science].
104. Sudipta Ghosh, Rajesh K Singh, Vikash Kumar Dubey and Latha Rangan . Antileishmanial Activity of Labdane Diterpenes Isolated from Alpinia nigra Seeds. Letters in Drug Design and Discovery, 2017, 14, 119-124( [Publisher: Bentham Science].
103. Shilpa N. Patere, Pankaj O. Pathak, Anil Kumar Shukla, Rajesh Kumar Singh, Vikash Kumar Dubey, Miten J. Mehta, Anand G. Patil, Vikram Gota, Mangal S. Nagarsenker.. Surface-Modified Liposomal Formulation of Amphotericin B: In vitro Evaluation of Potential Against Visceral Leishmaniasis. AAPS PharmSciTech. 2017, 18, 710-720. [Publisher: Springer@ American Association of Pharmaceutical Scientists].
102. Kartikeya Tiwari , Ritesh Kumar and Vikash Kumar Dubey* . Biochemical characterization of dihydroorotase of Leishmania donovani: Understanding pyrimidine metabolism through its inhibition. Biochimie, 2016, 131, 45-53 [*Corresponding author; Publisher: Elsevier].
101. Ritesh Kumar, Pratyajit Mohapatra and Vikash Kumar Dubey* . Exploring realm of proteases of Leishmania donovani genome and gene expression analysis of proteases under apoptotic condition . Journal of Proteomics & Bioinformatics , 2016, 9: 200-208. doi:10.4172/ jpb.1000407 [*Corresponding author; Publisher: Omics Journal]
100. Ruchika Bhardwaj , Sanjeev Kumar Singh and Vikash Kumar Dubey* . Localization studies on LdBPK _070020, a conserved protein, of Leishmania donovani. Journal of Vector Borne Diseases, 2016, 53, 375-378. [*Corresponding author; Publisher: Medknow@ Indian Council of Medical Research]
99. Shyamali Sarma, Vikash K Dubey and Vijayanand Suryakant Moholkar . Kinetic and thermodynamic analysis (with statistical optimization) of hydrogen production from crude glycerol using Clostridium pasteurianum. International Journal of Hydrogen Energy, 2016, 41, 19972–19989 [Publisher: Elsevier]
98. Shalini Singh and Vikash Kumar Dubey*. Quantitative proteome analysis of Leishmania donovani under spermidine starvation. Plos One, 2016 PLoS ONE 11(4): e0154262. doi:10.1371/journal.pone.0154262 [*Corresponding author].
97. Ruchika Bhardwaj, Ritesh Kumar, Sanjeev Kumar Singh, Chandrabose Selvaraj and Vikash Kumar Dubey*. Understanding the importance of conservative hypothetical protein LdBPK_070020 in Leishmania donovani and its role in subsistence of the parasite. Archives of Biochemistry and Biophysics, 2016, 596, 10-21[*Corresponding author; Publisher: Elsevier].
96. Klionsky DJ, Abdelmohsen K, Abe A, Abedin , MJ, Abeliovich H,---(-----)--- Vikash Kumar Dubey,---(--------)--- Zughaier SM. Guidelines for the use and interpretation of assays for monitoring autophagy, Autophagy. 2016, 12, 1-222
95. Anil K. Saikia*, Sabera Sultana, Ngangbam Renubala Devi,Manash J. Deka,Kartikeya Tiwari, Vikash K. Dubey* Diastereoselective Synthesis of Substituted Hexahydrobenzo[de]isochromans and their Evaluation as Antileishmanial activity, Organic & Biomolecular Chemistry, 2016, 14,:970-9.[Publisher: The Royal Society of Chemistry]
94. Mousumi Das, Shalini Singh and Vikash Kumar Dubey*. Novel inhibitors of ornithine decarboxylase of Leishmania parasite (LdODC): The parasite resists LdODC inhibition by over-expression of spermidine synthase. Chem Biol Drug Des . 2016, 87, 352-360 [*Corresponding author; Publisher: Wiley]
93. Shalini Singh , Sitrarasu Vijaya Prabhu, Venkatesan Suryanarayanan, Ruchika Bhardwaj, Sanjeev Kumar Singh and Vikash Kumar Dubey*. Molecular docking and structure based virtual screening studies of CAAX prenyl protease I &II. Journal of Molecular Structure and Dynamics, 2016, 34, 2367-86. [*Corresponding author; Publisher: Taylor and Francis]
92. Sushant Singh and Vikash Kumar Dubey*. Multiwalled carbon nanotube-Superoxide dismutase conjugate towards alleviating induced oxidative stress . International Journal of Peptide Research and Therapeutics , 2016, 22, 171-177 [*Corresponding author; Publisher: Elsevier]
91. Mousumi Das, Gundappa Saha and Vikash Kumar Dubey*. Novel leads against miltefosine unresponsive Leishmania donovani . Antimicrobial Agents and Chemotherapy , 2015, 59, 7826-9 [*Corresponding author; Publisher: American Society of Microbiology]
90. Shalini Singh, Shyamali Sarma , Shashank P Katiyar , Mousumi Das , Ruchika Bhardwaj , Durai Sundar, Vikash Kumar Dubey*. Probing molecular mechanism of hypericin induced parasitic death: An insight into role of spermidine beyond redox metabolism of Leishmania. Antimicrobial Agents and Chemotherapy, 2015, 59,15-24. [*Corresponding author; Publisher: American Society of Microbiology].
89. Mousumi Das, Ritesh Kumar and Vikash Kumar Dubey*. Ornithine decarboxylase of Leishmania donovani: Biochemical properties and possible role of N-terminal extension . Protein and Peptide Letters , 2015, 22,:130-6 [*Corresponding author; Publisher: Bentham Science ].
88. Prakash Saudagar and Vikash Kumar Dubey*. Carbon Nanotube Based Betulin Formulation shows better efficacy against Leishmania parasite . Parasitology International, 2014, 63, 772-6 [*Corresponding author; Publisher: Elsevier]
87. Prakash Saudagar, Shyam Lal Mudavath, Pipas Saha, Anil K. Saikia, Shyam Sundar and Vikash Kumar Dubey*. In vivo assessment of antileishmanial property of 4-(4,4,8-Trimethyl-7-oxo-3-oxabicyclo[3.3.1]non-2-yl)-benzoic acid methyl ester, an oxabicyclo[3.3.1]nonanones. Letters in Drug Design and Discovery, 2014,11, 937-939 [*Corresponding author; Publisher: Bentham Science ].
86. Saudagar Prakash and Vikash Kumar Dubey*. Molecular Mechanisms of In vitro Betulin Induced Apoptosis of Leishmania donovani. American Journal of Tropical Medicine and Hygiene . 2014, 90, 354-60 [*Corresponding author; Publisher: American Society of Tropical Medicine and Hygiene ].
85. Vidhyadhar N, Sushant Singh, Abhay N Singh, Vikash Kumar Dubey*. Procerain B, a cysteine protease from Calotropis Procera, requires N-terminus pro-region for activity: cDNA cloning and expression with pro-sequence. Protein Expression and Purification. 2014, 103C:16-22.[*Corresponding author; Publisher: Elsevier]
84. Saravanan Parameswaran, Prakash Saudagar, Vikash Kumar Dubey, Sanjukta Patra. Discovery of novel anti-leishmanial agents targeting LdLip3 lipase. Journal of Molecular Graphics and Modelling 2014, 49, 68–79 [Publisher: Elsevier].
83. Saravanan Parameswaran, Vikash Kumar Dubey, Sanjukta Patra. Emulating structural stability of Pseudomonas mendocina lipase: in silico mutagenesis and moleular dynamics studies. Journal of Molecular Modeling 2014, 20 , 2501 [Publisher: Springer].
82. Mousumi Das, Saudagar Prakash, Shyam Sundar and Vikash Kumar Dubey*. Miltefosine unresponsive Leishmania donovani has better ability of resist reactive oxygen species. FEBS Journal, 2013, 280, 4807–4815 [*Corresponding author; Publisher: Wiley-Blackwell on behalf of the Federation of European Biochemical Societies ].
81 Saudagar Prakash, Pipas Saha , Anil K. Saikia and Vikash Kumar Dubey*. Molecular mechanism underlying antileishmanial effect of oxabicyclo[3.3.1]nonanones: Inhibition of key redox enzymes of the pathogen. European Journal of Pharmaceutics and Biopharmaceutics. 2013, 85, 569-577 [*Corresponding author; Publisher: Elsevier].
80. Sudipta Hazra, Subhalakshmi Ghosh, Madhushree Das Sarma, Mousumi Das, Saudagar Prakash, Vikash Kumar Dubey, Shyam Sundar, Banasri Hazra . Evaluation of a diospyrin derivative as antileishmanial agent and potential modulator of ornithine decarboxylase of Leishmania donovani. Experimental Parasitology, 2013, 135,:407-413 [Publisher: Elsevier].
79. Nandini Sarkar and Vikash Kumar Dubey. Exploring critical determinants of protein amyloidogenesis: A review . Journal of Peptide Science, 2013, 19:529-36 [Publisher: Wiley InterScience]
78. Sushant Singh, Abhay Narayan Singh, Anil Verma and Vikash Kumar Dubey*. Biodegradable Polycaprolactone (PCL) Nanosphere Encapsulating Superoxide Dismutase and Catalase Enzymes. Applied Biochemistry and Biotechnology, 2013, 171,1545-58. [*Corresponding author; Publisher: Springer ]
77. Abhay Narayan Singh, Prity Yadav and Vikash Kumar Dubey*. cDNA cloning and molecular modelling of Procerain B, a novel cysteine protease isolated from Calotropis procera. PLOS ONE, 2013, 8(3): e59806. doi:10.1371/journal.pone.0059806 [*Corresponding author]
76. Abhay Narayan Singh, Sushant Singh and Vikash Kumar Dubey*. Immobilization of Procerain B, a Cysteine Endopeptidase, on Amberlite MB-150 Beads. PLoS ONE 2013, 8(6): e66000.doi: 10.1371/journal.pone.0066000 [*Corresponding author]
75. Sushant Singh, Abhay Narayan Singh, Anil Verma and Vikash Kumar Dubey*. A novel superoxide dismutase from Cicer arietinum L. seedlings: purification and characterization. Protein and Peptide Letters. 2013, 20, 741-8. [*Corresponding author; Publisher: Bentham Science].
74. Sonali Seth, Debamitra Chakrovorty, Vikash Kumar Dubey and Sanjukta Patra. An insight into plant lipase research – challenges encountered. Protein Expression and Purification. 2013 95C: 13-21 [Publisher: Elsevier].
73. N. K. Prasanna Kumari, Vikash Kumar Dubey and Medicherla V. Jagannadham. SDS Induced Refolding of Pre-molten Globule State of Cryptolepain: Differences in Chemical and Temperature-Induced Equilibrium Unfolding of the Protein in SDS-Induced State. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences. 2013, 83, 71-80
72. Rajiv K. Verma, Vijay K. Prajapati, Girijesh K. Verma, Deblina Chakraborty, Shyam Sundar, Madhukar Rai, Vikash Kumar Dubey* and Maya Shankar Singh.* Molecular Docking and in vitro Antileishmanial Evaluation of Chromene-2-thione Analogues. ACS Medicinal Chemistry Letters. 2012, 3, 243-247. [*Joint corresponding author; Publisher: American Chemical Society].
71. Anil K Shukla, Sanjukta Patra and Vikash Kumar Dubey*. PEGylated nanospheres encapsulating antileishmanial drugs for their specific macrophage targeting, reduced toxicity and deliberate intracellular release. Vector-Borne and Zoonotic Diseases, 2012, 12, 953-60 [*Corresponding author]
70. Anil K Shukla, Sanjukta Patra and Vikash Kumar Dubey*. Iridoid glucosides from Nyctanthes arbortristis results in increased Reactive Oxygen Species and cellular redox homeostasis imbalance in Leishmania parasite. European Journal of Medicinal Chemistry , 2012, 54, :49-58 [*Corresponding author; Publisher: Elsevier].
69. Neha Sharma, Anil Kumar Shukla, Mousumi Das and Vikash Kumar Dubey*. Evaluation of plumbagin and its derivative as potential modulator of redox thiol metabolism of Leishmania parasite. Parasitology Research, 2012, 110, 341-348 [*Corresponding author; Publisher: Springer]
68. Abhinav Grover, Shashank Prakash Katiyar, Jeyaraman Jeyakanthan, Vikash Kumar Dubey and Durai Sundar. Blocking protein kinase C signaling pathway: mechanistic insights into the anti-leishmanial activity of prospective herbal drugs from Withania somnifera. BMC Genomics 2012;13 Suppl 7:S20.
67. Ruchika Bhardwaj, Prakash Saudagar and Vikash Kumar Dubey*. Nanobiosciences: A contemporary line for Antiparasitic Drug. Molecular and Cellular Pharmacology, 2012, 4, 97-103 [*Corresponding author].
66. Deblina Chakraborty, Parameswaran Saravanan, Sanjukta Patra and Vikash Kumar Dubey*. Studies on ornithine decarboxylase of Leishmania donovani: Structure modeling and inhibitor docking. Medicinal Chemistry Research, 2012, 167, 439-61 [*Corresponding author; Publisher: Springer].
65. Parameswaran Saravanan, Vikash Kumar Dubey and Sanjukta Patra. Targeting essential cell wall lipase Rv3802c for potential therapeutics against tuberculosis. Journal of Molecular Graphics and Modelling, 2012, 38, 235-42 [Publisher: Elsevier].
64. Manjeet Kumar, Nandini Sarkar, and Vikash Kumar Dubey*. Evaluating quinacrine as a potential amyloid imaging compound: studies on hen egg white lysozyme as model system. Protein and Peptide Lett., 2012, 19, 826-31 [*Corresponding author;Publisher: Bentham Science].
63. Abhinav Grover, Sushil Kumar Shakyawar, Saudagar Prakash, Vikash Kumar Dubey and Durai Sundar. Epitopic analysis of potential vaccine candidate in Leishmania infantum for development of human vaccine. Letters in Drug Design and Discovery, 2012, 9, 698-705 [Publisher: Bentham Science].
62. Abhinav Grover, Shashank Prakash Katiyar, Jeyaraman Jeyakanthan, Vikash Kumar Dubey and Durai Sundar. Mechanistic insights into the dual inhibition strategy for checking leishmaniasis. Journal of Biomolecular Structure & Dynamics. 2012, 30, 474-87 [Publisher: Taylor and Francis].
61. Sushant Singh, Anil Verma and Vikash Kumar Dubey*. Aluminium induced oxidative stress in germinating chickpea ( Cicer arietinum L.) seeds. Brazilian Journal of Plant Physiology, 2012, 24, 47-54 [*Corresponding author].
60. Parameswaran Saravanan, Vikash Kumar Dubey, Sanjukta Patra. Potential Selective Inhibitors against Rv0183 of Mycobacterium tuberculosis Targeting Host Lipid Metabolism. Chemical Biology & Drug Design. 2012, 79, 1056-62 [Publisher: Wiley InterScience] The article is featured as a key scientific article on the Global Medical Discovery web site.
59. Debamitra Chakravorty, Parameswaran Saravanan, Vikash Kumar Dubey, Sanjukta Patra. Unraveling the rationale behind organic solvent stability of lipases. Applied Biochemistry and Biotechnology, 2012, 167, 439 461 [Publisher: Springer]
58. Abhinav Grover, Shashank Prakash Katiyar, Sanjeev Kumar Singh, Vikash Kumar Dubey and Durai Sundar. A Leishmaniasis study: structure-based screening and molecular dynamics mechanistic analysis for discovering potent inhibitors of spermidine synthase. Biochimica et Biophysica Acta - BBA: Proteins and Proteomics, 2012, 1824, 1476-83 [Publisher: Elsevier].
57. Santhosh K. Venkatesan and Vikash Kumar Dubey*. Footprinting of Inhibitor Interactions of in silico identified inhibitors of trypanothione reductase of Leishmania parasite. TheScientificWorldJOURNAL, 2012, Article ID 963658, 13 doi:10.1100/2012/963658 [*Corresponding author]
56. Saudagar Prakash and Vikash Kumar Dubey*. Cloning, expression, characterization, and inhibition studies on trypanothione synthetase, a drug target enzyme, from Leishmania donovani. Biological Chemistry, 2011, 392, 1113-22. [*Corresponding author;Publisher:Walter de Gruyter]
55. Nandini Sarkar; Manjeet Kumar; Vikash Kumar Dubey*. Rottlerin dissolves pre-formed protein amyloid: A study on hen egg white lysozyme. Biochimica et Biophysica Acta-General Subjects, 2011,1810, 809-814 [*Corresponding author; Publisher: Elsevier]
54. Abhay Narayan Singh, Neeraj Suthar, Sushant Singh, and Vikash Kumar Dubey*. Glutaraldehyde activated chitosan matrix for immobilization of a novel cysteine protease, procerain B. Journal of Agricultural and Food Chemistry (ACS), 2011, 59, 6256-62 [*Corresponding author; Publisher:American Chemical Society]
53. Nandini Sarkar, Manjeet Kumar and Vikash Kumar Dubey*. Effect of sodium tetrathionate on amyloid fibril: Insight in to the role of disulfide bond in amyloid progression. Biochimie, 2011, 2011. 93, 962-968 [*Corresponding author; Publisher: Elsevier]. The article is featured as a key scientific article on the Global Medical Discovery web site
52. Nandini Sarkar, Manjeet Kumar and Vikash Kumar Dubey*. Exploring possibility of promiscuity of amyloid inhibitor: Studies on effect of selected compounds on folding and amyloid formation of proteins. Process Biochemistry, 2011, 46, 1179-1185 [*Corresponding author; Publisher: Elsevier].
51.Anil K Shukla, Sanjukta Patra and Vikash Kumar Dubey*. "Evaluation of selected antitumor agents as subversive substrate and potential inhibitor of trypanothione reductase: An alternative approach for chemotherapy of Leishmaniasis". Molecular and Cellular Biochemistry, 2011, 352, 261-70 [*Corresponding author; Publisher: Springer] Research Highlight of the article published in Nature India.
50. Anil K Shukla, Sanjukta Patra and Vikash Kumar Dubey*. Deciphering molecular mechanism underlying antileishmanial activity of Nyctanthes arbortristis, an Indian medicinal plant. Journal of Ethnopharmacology, 2011, 134, 996-998 [*Corresponding author; Publisher: Elsevier]
49. Jihun Lee, Sachiko I. Blaber, Vikash K. Dubey and Michael Blaber. A polypeptide "building block" for the -trefoil fold identified by "top-down symmetric deconstruction. Journal of Molecular Biology, 2011, 407, 744-63. [Publisher: Elsevier].
The article is featured as a key scientific article on the Global Medical Discovery web site. The article is selected by the Faculty of 1000 (F1000), which places the work in the top 2% of published articles in biology and medicine.
[Cover page article April 15, 2012 issue of Journal of Molecular Biology ].
48. Bankapallai Leela Krishna, Abhay Narain Singh, Sanjukta Patra* and Vikash Kumar Dubey*. Purification, characterization and immobilization of urease from Momordica charantia seeds, Process Biochemistry, 2011, 46 , 1486-1491[*Corresponding authors; Publisher: Elsevier]
47. Abhay Narain Singh and Vikash Kumar Dubey*. Exploring applications of procerain B, a novel protease from Calotropis procera, and characterization by N-terminal sequencing as well as peptide mass fingerprinting. Applied Biochemistry and Biotechnology, 2011, 164, 573-80. [*Corresponding author; Publisher: Springer]
46. Anil K Shukla, Sanjukta Patra; Vikash Kumar Dubey*. Biophysical and folding parameters of trypanothione reductase from Leishmania infantum, Applied Biochemistry and Biotechnology, 2011, 165, 13-23 [*Corresponding author; Publisher: Springer]
45. Santhosh K. Venkatesan, Prakash Saudagar and Vikash Kumar Dubey*. Identification of novel inhibitor of Trypanothione synthtase from two Leishmania species: comparative in silico analysis. Journal of Proteins and Proteomics, 2011, 2, 41-48.
44. Neeraj Suthar and Vikash Kumar Dubey*. In silico approach to counter Leishmania donovani by targeting cysteine protease B : Structure modeling and inhibitor docking. Global Journal of Biochemistry,2011, 2, 49-58.
43. Santhosh K. Venkatesan, Prakash Saudagar, Anil Kumar Shukla and Vikash Kumar Dubey* Screening natural products database for identification of potential antileishmanial chemotherapeutic agents.Interdisciplinary Sciences: Computational Life Sciences, 2011, 3, 1-15 [*Corresponding author; Publisher: Springer]
42. Parameswaran Saravanan, Santhosh K. Venkatesan, C Gopi Mohan, Sanjukta Patra* and Vikash Kumar Dubey* Mitogen-activated protein kinase 4 of Leishmania parasite as a therapeutic target. European Journal of Medicinal Chemistry, 2010, 45, 5662-5670 [*Corresponding authors; Publisher: Elsevier]
41. Debamitra Chakravorty, Parameswaran Saravanan, Vikash Kumar Dubey and Sanjukta Patra. In Silico Characterization of Thermostable Lipases. Extremophiles, 2011, 15, 89-103 [Publisher: Springer].
40. Sushil Kumar Shakyawar, Arun Goyal, Vikash Kumar Dubey* Genome analysis of selected foodborne pathogens for identification of drug targets. Current Trends in Biotechnology and Pharmacy, 2011, 5, 1134-1148.
39. Sushil Kumar Shakyawar, Arun Goyal, Vikash Kumar Dubey* Database of in silico Predicted Potential Drug Target Proteins in Common Bacterial Human Pathogens. American Journal of Drug Discovery and Development, 2011, 1, 70-74.
38.B. Praveen Kumar#, Sushant Singh# and Vikash Kumar Dubey*. Effect of Arsenic stress on Vigna radiate: A Biochemical studies. International Journal of Environmental Science and Engineering Research. 2010. 1, 1-4 [#Equal contribution]
37. Parameswaran Saravanan, Vikash Kumar Dubey and Sanjukta Patra. In silico characterization of thermoactive, alkaline and detergent-stable lipase from a Staphylococcus aureus strain. In Silico Biology, 2010, 10, 265–276
36. Santhosh Kannan, Anil Kumar Shukla and Vikash Kumar Dubey*. Molecular docking studies of selected tricyclic and quinone derivatives on trypanothione reductase of Leishmania infantum. Journal of Computational Chemistry, 2010, 31, 2463-2472 [*Corresponding author; Publisher: Wiley InterScience] Research Highlight of the article published in Nature India.
35. Alka Dwevedi, Vikash Kumar Dubey, Medicherla V. Jagannadham, Arvind M. Kayastha (2010) Insights into pH-Induced Conformational transition of b-Galactosidase from Pisum sativum leading to its Multimerization. Applied Biochemistry and Biotechnology, 162, 2294-2312 [Publisher: Springer]
34. Abhay Narain Singh, Anil Kumar Shukla, M.V. Jagannadham and Vikash Kumar Dubey*. Purification of a novel cysteine protease, procerain B, from Calotropis procera with distinct characteristics compared to procerain. Process Biochemistry, 2010, 45, 399-406 [*Corresponding author; Publisher: Elsevier]
33. Nandini Sarkar and Vikash Kumar Dubey*. Protein nano-fibrilar structure and associated diseases. Current Proteomics, 2010, 7, 116-120. [*Corresponding author Publisher: Bentham Science]
32. Anil K Shukla, Bishal K Singh, Sanjukta Patra, Vikash Kumar Dubey.* Rational approaches for drug designing against leishmaniasis. Applied Biochemistry and Biotechnology, 2010, 160, 2208-2218 [*Corresponding author; Publisher: Springer]
31. Nandini Sarkar, Abhay Narain Singh and Vikash Kumar Dubey*. Effect of curcumin on amyloidogenic property of molten globule like intermediate state of 2,5-Diketo-D-Gluconate Reductase A. Biological Chemistry, 2009, 390, 1057-1061. [*Corresponding author; Publisher: Walter de Gruyter]
30. Neeraj Suthar, Arun Goyal and Vikash Kumar Dubey. Identification of potential drug targets of Leishmania Infantum by in-silico genome analysis. Letters in Drug Design and Discovery, 2009, 6, 620-622, [*Corresponding author; Publisher: Bentham Science]
29. Bishal Kumar Singh and Vikash Kumar Dubey*. In silico studies on tryparedoxin peroxidase of Leishmania infantum: Structural aspects. Current Pharmaceutical Biotechnology, 2009, 10, 626-630. [*Corresponding author Publisher: Bentham Science]
28. Syed Baquer Rizvi , Anil Kumar Shukla and Vikash Kumar Dubey.* A Simple method based on multiple alignment and phylogeny to derive a correlation between the protein fold and sequence via motif search. Interdisciplinary Sciences: Computational Life Sciences, 2009, 1, 235-243. [*Corresponding author; Publisher: Springer].
27. Nandini Sarkar Pramod Kumar Srivastava and Vikash Kumar Dubey*. Understanding the Language of Vitamin C. Current Nutrition & Food Science, 2009, 5, 53-55. [*Corresponding author; Publisher: Bentham Science]
26. Vikash Kumar Dubey*. Structural Genomics on Membrane Proteins. Applied Biochemistry and Biotechnology, 2009, 157, 111. [Corresponding author Publisher: Springer].
25. Anil Kumar Shukla, Utapl Bora and Vikash K. Dubey*. Functional Adaptations in Fibroblast Growth Factor (FGFs) Family. Journal of Proteins and Proteomics, 2009, 1, 11-13. [*Corresponding author; Publisher: Serial Publication (India)]
24. Naresh Kasoju , Shahin Sharif Ali, Vikash Kumar Dubey and Utpal Bora*. Exploiting the potential of Collagen as a Natural Biomaterial in Drug Delivery. Journal of Proteins and Proteomics, 2009, 1, 31-36 [Publisher: Serial Publication (India)]
23. Ritu Tomar, Vikash Kumar Dubey,* and M.V. Jagannadham* Biophysical characterization and folding studies of plant protease, Wrightin: identification folding intermediate under different conditions. The Protein Journal, 2009, 28:213-223 [*Co- corresponding author; Publisher: Springer]
22. Monu Pande, N K Prasanna Kumari, Vikash Kumar Dubey*, Pinky Tripathi, and M.V. Jagannadham*. Stability and Unfolding Studies on Alkaline Denatured State (Ip) of Pepsin. Process Biochemistry, 2009, 44, 906-911 [*Co-corresponding author; Publisher: Elsevier]
21. Ritu Tomar, Vikash Kumar Dubey, and M.V. Jagannadham* Effect of Alkyl Alcohols on partially unfolded state of Proteinase K: differential stability of alpha-helix and beta-sheet rich regions of the enzyme. Biochimie, 2009, 91, 951-960. [Publisher: Elsevier]
20. Bishal K. Singh, Nandini Sarkar, M.V. Jagannadham and Vikash K. Dubey*. Modeled Structure of Trypanothione Reductase of Leismania infantum. BMB Reports Previously known as J Biochem Mol Biol. And listed in journal citation report 2008 with old name), 2008, 41, 444-447. [*Corresponding author; Publisher: Korean Society of Biochemistry and Molecular Biology]
19. Vikash K Dubey* and M.V Jagannadham. Roles for cavities in protein structure: New insights. Current Proteomics, 2008, 5, 157-160 [*Corresponding author; Publisher: Bentham Science].
18. Bishal K. Singh, Nandini Sarkar and Vikash K. Dubey*. Modeled Structure of Trypanothione synthetase of Leishmania infantum for development of novel therapeutics for leishmaniasis. Current Trends in Biotechnology and Pharmacy, 2008, 2, 390-395. [*Corresponding author; Publisher: Association of Biotechnology and Pharmacy (India)]
17. Jihun Lee, Vikash K Dubey, Liam M Longo, Michael Blaber. Logical OR Redundancy within the Asx-Pro-Asx-Gly Type I b-turn Motif. Journal of Molecular Biology, 2008, 377, 1251-1264. [Publisher: Elsevier].
16. Vikash K. Dubey*, Bishal K Singh, Nandini Sarkar, Monu Pande and M.V Jagannadham. Biophysical characterization of Fibroblast Growth Factor homologous Factor-1b (FHF-1b): Sodium dodecyl sulfate promotes two state folding. Protein and Peptide Lett.,2008, 15, 215-218 [*Corresponding author;Publisher: Bentham Science]
15. Vikash K. Dubey*, Monu Pande, Bishal Kumar Singh and Medicherla V. Jagannadham. Realm of Papain-Like Proteases: Applications of their Inhibitors. Afr. Journal of Biotechnology, 2007, 6, 1077-1086. [*Corresponding author; Publisher: Academic Journals]
14. Vikash Kumar Dubey, Jihun Lee, Thayumana Somasundaram, Sachiko Blaber and Michael Blaber. Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N- and C-termini b-strand interactions. Journal of Molecular Biology, 2007, 371, 256-268. [Publisher: Elsevier]
13. Sreedevi Nallamsetty, Vikash K. Dubey, Monu Pande, P. K. Ambasht and M.V. Jagannadham. Accumulation of partly folded states in the equilibrium unfolding of ervatamin A: Spectroscopic description of the native, intermediate, and unfolded states. Biochimie, 2007, 89, 1416-24. [Publisher: Elsevier;]
12. Monu Pande, Vikash Kumar Dubey, Vishal Sahu and M.V. Jagannadham. Conformational Plasticity of Cryptolepain: Accumulation of Partially Unfolded States in Denaturants induced Equilibrium Unfolding. Journal of Biotechnology, 2007, 131, 404-414. [Publisher: Elsevier]
11. Monu Pande, Vikash K. Dubey, and Medicherla V. Jagannadham. Crystallization and preliminary x-ray analysis of cryptolepain: A novel glycosylated serine protease from Cryptolepis buchanani. Acta Crystallographica, 2007, F63, 74-77 [Publisher: International Union of Crystallography;]
10. Jihun Lee, Vikash Kumar Dubey, Thayumanasamy Somasundaram and Michael Blaber. Conversion of type I 4:6 to 3:5 ?-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function. Proteins: Structure Function Bioinformatics, 2006, 62, 686-697. [Publisher: Wiley InterScience]
9. Monu Pande, Vikash K. Dubey, Subhash Chandra Yadav and Medicherla V. Jagannadham. A Novel Serine Protease Cryptolepain, from Cryptolepis buchanani: Purification and Biochemical Characterization. Journal of Agricultural and Food Chemistry (ACS), 2006, 27, 10141-10150. [Publisher: American Chemical Society]
8. Vikash Kumar Dubey, Monu Pande and M.V. Jagannadham. Snapshots of Protein Folding Problem: Implications of Folding and Misfolding Studies. Protein and Peptide Lett., 2006, 13, 883- 888. [Publisher: Bentham Science].
7. Vikash K. Dubey, Ashu Saha, M.V. Jagannadham and A.M. Kayastha. Effect of Organic solvent on molten globule state of procerain: b-sheet to l-helix switchover in presence of TFE. Protein and Peptide Lett., 2006, 13, 545-547. [Publisher: Bentham Science]
6. Vikash K. Dubey, Jihun Lee, and Michael Blaber. Redesigning Symmetry-Related "Mini-Core" Regions of FGF-1 to Increase Primary Structure Symmetry: Thermodynamic and Functional Consequences of Structural Symmetry. Protein Science, 2005, 14, 2315-2323. [Publisher: Protein Society (USA)]
5. Carlo Travaglini-Allocatelli, Stefano Gianni, Vikash K. Dubey, Alessandro Borgia, Adele Di Matteo, Daniele Bonivento, Francesca Cutruzzola, Kara L. Bren, Maurizio Brunori. An obligatory intermediate in the folding pathway of cyctochrome C552 from Hydrogenobacter thermophilus. J. Biol Chem., 2005, 280, 25729-25734. [Publisher: American Society of Biochemistry and Molecular Biology].
4. Stephen R. Brych, Vikash K. Dubey, Ewa Bienkiewicz, Jihun Lee, Timothy M. Logan and Michael Blaber. Symmetric primary and tertiary structure mutations within a symmetric superfold: A solution and not a constraint to achieving a foldable polypeptide? Journal of Molecular Biology, 2004, 344, 769-780. [Publisher: Elsevier ]
3. Monica Sundd, Suman Kundu, Vikash Kumar Dubey and M.V. Jagannadham. Unfolding of ervatamin C in the presence of organic solvents: Sequential unfolding of the protein in O-state. Journal of Biochemistry and Molecular Biology, 2004, 37, 586-596. [Publisher:Korean Society of Biochemistry and Molecular Biology]
2. Vikash Kumar Dubey and M.V. Jagannadham. Differences in the unfolding of procerain induced by pH, GuHCl, urea and temperature. Biochemistry (ACS), 2003, 42, 12287-12297. [Publisher: American Chemical Society]
1. Vikash Kumar Dubey and M.V. Jagannadham. Procerain, a stable cysteine protease from Calotropis procera. Phytochemistry, 2003, 62, 1057-1071. [Publisher: Elsevier]
S.No. | Author/Co-authors/Editor | Year | Title of Book(s)/ Book Chapters | Details of Publisher |
1 | Timir Tripathi, Vikash Dubey | 2022 | Advances in Protein Molecular and Structural Biology Methods 1st Edition - January 14, 2022 (Book) | Elsevier |
2 | Gundappa Saha, Sukanya Ghosh, Vikash Kumar Dubey, Prakash Saudagar | 2022 | Gene Alterations Induced by Glutamine (Q) Encoding CAG Repeats Associated with Neurodegeneration. In: Pereira, G.C. (eds) Gene, Drug, and Tissue Engineering. Methods in Molecular Biology, vol 2575. | Humana, New York, NY.
Online ISBN978-1-0716-2716-7 |
3 | Shyamali Sarma, Vikash Kumar Dubey, Vijayanand S. Moholkar, | 2022 | hapter 16 - Circular bioeconomy for biodiesel industry: Upgradation of waste glycerol to value-added products, Editor(s): Sunita Varjani, Ashok Pandey, Thallada Bhaskar, S. Venkata Mohan, Daniel C.W. Tsang, Biomass, Biofuels, Biochemicals, Pages 419-438, https://doi.org/10.1016/B978-0-323-89855-3.00017-0. |
Elsevier ISBN 9780323898553, |
4 | Gundappa Saha, Prakash Saudagar and Vikash Kumar Dubey | 2019 | Virus like particles: nano-carriers in targeted therapeutics In: Encapsulation of Active Molecule and their Delivery systems | Publisher: Elsevier ISBN 978-0-12-819363-1 |
5 | Bishal Kumar Singh and Vikash Kumar Dubey | 2014 | Leishmaniasis: Trypanothione metabolism as potential drug targets for rational drug designing (Chapter 20). In Recent Developments in Biotechnology (J.N. Govil Ed). Vol 9; pp 455-471 | Studium Press LLC, USA ISBN: 1-62699-024-7 |
6 | Vikash Kumar Dubey and Suman Kundu | 2014 | Processing of Recombinant Proteins (Chapter 34), In Gene and its Engineering. H. K. Das.Ed | Wiley ISBN: 978-81-265-4928-3 |
7 | Ritesh Kumar, Shalini Singh and Vikash Kumar Dubey | 2015 | Bioinformatics Tools to Analyze Proteome and Genome Data, In: Advances in the Understanding of Biological Sciences Using Next Generation Sequencing (NGS) Approaches Editors: Sablok , G., Kumar , S., Ueno , S., Kuo , J., Varotto , C. Page 179-194 | Springer ISBN: 978-3-319-17157-9 |
9 | Prepared 40 LECTURES online for National program for Enhanced learning (NPTEL), an initiative of IITs and IISc (funded by MHRD).http://nptel.ac.in/courses/102103017/ | |||
10 | Database prepared: http://www.iitg.ac.in/vdubey/DTPdB/index.php |
Year | Title | International/ National | Status |
2024 | An anti-parasitic composition for the management of Leishmaniasis. Application No. 202411054976 |
National | Filed |
2022 |
A thrombin receptor antagonist for management of leishmaniasis. Application No.: 202211067169 |
National
|
Published |
2022 | An Anti-Leishmanial Steroidal Alkaloid Drug Compound (Appli. No. 208211049337) | National | Published |
2013 | Oxabicyclo derivatives as novel antileishmanial compound. (63/KOL/2013 ) | National | Published but award Pending |
2012 | Mutants of human fibroblast growth factor having increased stability and/or mitogenic potency . USA Patent issued [No. 8,119,776 (2012)] | US patent/ International/ | Awarded |
2012 | Mutants of human fibroblast growth factor having increased stability and/or mitogenic potency . USA Patent issued [No. 8,153,770 (2012)]. | US patent/ International/ | Awarded |
2012 | Mutants of human fibroblast growth factor having increased stability and/or mitogenic potency . USA Patent issued [No. 8,153,771 (2012)]. | US patent/ International/ | Awarded |
2010 | Iridoid glucosides from Nyctanthes arbortristis as new class of inhibitor of Trypanothion reductase of leishmania parasite. (306/KOL/2010). | National | Pending |
2010 | Mutants of human fibroblast growth factor having increased stability and/or mitogenic potency. USA Patent issued [No. 7,659,379 (2010)]. | US patent/ International/ | Awarded |
2009 | A novel cysteine protease, procerain B, from Calotropis procera. (1346/KOL/2009). | National | Pending |
2009 | Mutant polypeptides of Fibroblast Growth Factor-1. USA Patent issued [No. 7,595,296 (2009)]. | US patent/ International/ | Awarded |
2010 | Mutant polypeptides of Fibroblast Growth Factor-1. USA Patent issued [No. 7696171(2010)]. | US patent/ International/ | Awarded |
2010 | Mutant polypeptides of Fibroblast Growth Factor-1. USA Patent issued [No. 7776825 (2010)]. | US patent/ International/ | Awarded |
Administrative experiences outside the Institute
--August 2024: External Expert in Board of studies, Department of Biochemistry, Banaras Hindu University (two years from 21.08.2024)
-August 2023 onward:- DST-Expert Committee member for VAIBHAV Research Programme
-July 2023 onward:-Expert member of the AICTE Expert Visit Committee for conducting physical visit to AICTE approved Institutions/ Universities.
-December 2022 onward:- Special Selection Board to review and select the Senior Research Associates in the Life Science Domain under the POOL Scientist scheme of CSIR
-July 2021 onward:- SERB Expert Committee (Core Member), Life Sciences on (i) Start up Research Grant (ii) National Post-Doctoral Fellowship Schemes and (iii) Early Career Research Award Schemes
-April 2021:-Nominated as as continuous reviewer for CSIR-FIRST Scheme.
-October 2020: Member, DST Expert Panel/Task-force for COVID-19 related International project proposals (three years from October 2020)
-January 2019: Board of studies, Chemical Technology, Guru Gobind Singh Indraprastha University, Delhi (two years from 16.01.2019)
-December 2018: DBT-NER Technical Expert Committee (TEC) in the area of knowledge Generation and DISCOVERY Research, New Tool & Technology (three years from Dec. 2018)
-December 2018: DBT-NER Scientific and Technical Appraisal and Advisory Group (STAGE) (three years from Dec. 2018)
-August 2018: Subject Expert, Jharkhand Public Service Commission, Ranchi
-December 2018: Special Invitee, EMEQ Task Force Committee, SERB, Government of India
-July 2015 – May 2018: DBT Nominee for Institutional Biosafety Committee, National Research Centre on Pig, Indian Council of Agricultural Research, Guwahati
-Member, Faculty selection, sevaral IITs, State and Central Universities and NIT
-Reviewed Research projects for Italian Ministry of Health; BIRAC, CSIR, DBT, Govt of India; SERB, DST, Govt of India
-Reviewed projects for Shastri Indo-Canadian Institute
-PhD thesis reviewer of several institutes including BHU, CDRI, IICT, NII, JNU, NEHU, many IITs, NIPER, many Central Universities, Utkal University etc
Administrative experiences at IIT (BHU) Varanasi (May 2018 onward)
Dean (R&D). Jan. 2022 onward
-Coordinator, School of Biochemical Engineering: Feb., 2020
-Member, Finance Committee, IIT (BHU) : 12-March 2024 onward
-Associate Dean (Academic Affairs): June 2019 - Feb 2022
-BoG member, IIT (BHU): 1-January 2022 to 31-December 2023
-Member, Library Committee (2018-2019)
-Member, Departmental Faculty Affairs Committee, School of Biochemical Engg. (2018 onward)
-Member, Departmental Faculty Affairs Committee, Department of Architecture Planning and Design (2019-2021)
-Member, Purchase committee (2018-19)
-Member, Department postgraduate Committee (DPGC).
-Member, Department undergraduate Committee (DUGC)
Administrative experiences at IIT Guwahati (September 2006 - May 2018)
Period | Organisation | Nature of Responsibility | Designation |
August 2015 – May 15, 2018 | Centre for the Environment, IIT Guwahati | Overall administration of the centre | Head |
December 2014 – November 2015 | Student Welfare, IIT Guwahati | Coordinating welfare activities of students | Chairman |
November 2014 – April 2017 |
Red Ribbon Club, IIT Guwahati | HIV awareness among IIT Guwahati community | Faculty In-Charge (Nodal Programme Officer), Red Ribbon Club |
May 2009- May 2014 | National Programme for Technology Enhanced Learning (NPTEL) | Coordinating course development related to Biotechnology | Coordinator (Biotechnology subject) National Programme for Technology Enhanced Learning |
October 2007 to April 2009. | Department of Biotechnology, IIT Guwahati | All issues related to undergraduate courses of department | Member, Department Undergraduate Programme Committee: |
May 2009-May 2011 | Department of Biotechnology, IIT Guwahati | All issues related to undergraduate courses of department | Member Secretary: Department Undergraduate Programme Committee |
May 2009-May 2011 | IIT Guwahati | All issues related to undergraduate courses of the Institute | Member, Institute Undergraduate Programme Committee (IUPC): |
May 2011- May 2018 | Department of Biotechnology, IIT Guwahati | All issues related to undergraduate courses | Member Department Undergraduate Programme Committee |
December 2006 to April 2009. | Department of Biotechnology, IIT Guwahati | Writing all reports related to department | Coordinator: Departmental report writing: |
June 2012 -May 2013 | Department of Biotechnology, IIT Guwahati | Coordinating all equipment purchases for laboratory set-up | Coordinator, Purchase committee for Equipment (Biotechnology) |
June 2010-April 2011 | Department of Biotechnology, IIT Guwahati | Coordinating all issues related to space utilization, equipment purchases and repair | Coordinator: Technical committee, Department of Biotechnology |
March 2010-April 2012 | Department of Chemical Engineering, IIT Guwahati | All academics issue of Postgraduate students of the department | External member, Department Postgraduate Programme Committee: (Dept. of Chemical Engineering, IITG): |
May 2009 -May 2013 | Department of Biotechnology, IIT Guwahati | All academics issue of Postgraduate students of the department | Member: Department Postgraduate Programme Committee |
Sep. 2014-October 2015 | IIT Guwahati Club | Recreation and cultural activities of IIT Guwahati fraternity | Vice President: IIT Guwahati Club (IIT Guwahati director being President) |
-Very actively involved in GATE examination (pre examination confidential duty and post examination duty. -Member of various committees at IIT Guwahati (Campus well being committee; ant-ragging committee, convocation committee etc) -Member: Committee for space utilization: May 2013- May 2016 - Member: Technical committee, Department of Biotechnology : October 2007-May 2010. - Member: Faculty recruitment Committee of the department: May 2009-May 2010. - Faculty Advisor: 2005 B.Tech batch: October 2007- April 2009. - Member: Purchase committee of the Department (2007-08). |
Sponsored Projects @ IIT (BHU) Varanasi (May 2018 onward..)
Sponsoring Organisation | Period | Title of Project | PI, /Co-PI |
ICMR | 2021-2024 | Human IL-2 fused leishmanial trypanothione synthetase (TS) as protein vaccine candidates. | P.I |
CSIR | 2019 - 2023 (Ongoing) | How Beclin 1 mediates cross-talk between apoptosis and autophagy via its C- terminal fragment? | P.I |
ICMR | 2021-2024 (Ongoing) | Validation of glutathione synthetase from Leishmania donovani as new drug target for discovery of new drug candidate | P.I |
SERB | 2020- 2021 (Completed) | Re-purposing of approved drugs from DrugBank database for possible treatment for COVID-19 by targeting SARS-CoV-2 main protease. Short-term special call on COVID-19. Project duration as per SERB sanction was one year. Extended for 06 months (total duration 18 months) |
P.I |
IIT (BHU) Varanasi | 2018-2019 (Completed) | Engineering recombinant human IL-2 fused Leishmanial surface antigens. | P.I |
Sponsored Projects @ IIT Guwahati (2006-2018)
Sponsoring Organisation | Period | Title of Project | PI, /Co-PI |
DBT | 2015-18 (Completed) |
Unit of excellence in Molecular and Biochemical Parasitology: Investigation on evolutionary pressure for unique redox metabolism of Leishmania parasite | PI |
DBT | 2015-17 (Completed) |
Optimization of novel antileishmania scaffold 4-(4,4,8-Trimethyl-7-oxo-3-oxabicyclo[3.3.1]non-2-yl)-benzoic acid methyl ester, a oxabicyclo[3.3.1]nonanones: A mechanistic study | PI |
DBT | 2017-2020 |
Understanding the mechanism of ABC-type metal sequestering proteins: structure-based novel drug development against human pathogens |
Co-P.I |
DBT | 2014-2017 (Completed) |
Identification of novel drug targets of Leishmania donovani: Studies on CAAX prenyl protease I and II of the pathogen | PI |
DBT | 2012-2015 (Completed) |
X-ray crystallographic structure elucidation of key drug target enzymes of Leishmania donovani. | PI |
DBT | 2012-2015 (Completed) |
Studies on trypanothione synthetase, a key enzyme of redox metabolism of Leishmania donovani. | PI |
DST | 2012-2015 (Completed) |
Variation in proteome profile of legume plants in response to heavy metal toxicity. | PI |
DBT | 2011 – 2014 (Completed) |
Betraying the parasite's redox system: Studies on spermidine synthase of Leishmania donovani | PI |
DBT | 2011 - 2014 (Completed) |
Studies on Peptide-conjugated nanoparticles mediated antileishmanial drug delivery to macrophages. | PI |
DBT | 2010-2015 Extended for two years (2013-2015) (Completed) |
DBT-Innovative Young Scientist Award Deciphering the molecular mechanism underlying the activity of antitumor agents as antileishmanial agents and their potential for therapy. |
PI |
ICMR | 2011 - 2014 (Completed) |
An integrated computational and biochemical approach to target ornithione decarboxylase, a key enzyme involved in synthesis of trypanothione for antileishmanial drug discovery. | PI |
CSIR | 2009-2012 (Completed) |
Studies on effect of small molecule compounds on folding and amyloid formation of proteins | PI |
DBT | 2009-2012 (Completed) |
Studies on Trypanothione Reductase from Parasites: Structure, Function, Folding and Potential for Chemotherapy | PI |
DIT | 2008-2010 (Completed) | Development of novel therapeutics against leishmaniasis. | PI |
DBT | 2007-2010 (Completed) | Folding Studies of 2, 5-Diketo-D-gluconate Reductase | PI |
DST | 2007-2010 (Completed) | Structural Properties and folding mechanism of apocytichrome C552 from Hydrogenobactor Thermophilus (DST-SERC FAST Young Scientist Grant | PI |
DBT | 2010- | DBT-Bioinformatics Infrastructure facility | Co-Cordinator |
DBT | 2012-2015 (Completed) |
Studies on structure of enzymes and their interaction with nanostructured materials for bioelectronics devices and other applications. | CO-PI |
DBT | 2012-2015 (Completed) |
Structural and functional studies of translation initiation factor from Pyrococcus horikoshii. | CO-PI |
DBT | 2012-2015 (Completed) |
Structure, Function, Dynamics and structural studies on Matrix metalloprotenases | CO-PI |
DIT | 2007-2010 (Completed) | Protein stability prediction of lipases – in silico studies | CO-PI |
DBT | 2010-2013 (Completed) |
Biochemical and Functional Characterization of RIO kinase (s) from as a potential drug target. | CO-PI |
Research Group at IIT (BHU) Varanasi:
Dr. Ehasanullah Khan, Postdoctoral Fellow
Mr. Manas Kumar (PhD Student)
Ms. Naveena Menpadi (PhD Student)
Mr. kaushal Bora (joint PhD with IIT Guwahati - Home Institute IIT (BHU) Varanasi)
Mr. Shiv Kumar (PhD Student)
Ms. Atreyee Chatterjee (PhD Student)
Ms. Ankita Mondal (PhD Student)
Ms. Anindita Sengupta (joint PhD with IIT Guwahati - Home Institute IIT Guwahati)
Lab Alumni at IIT (BHU) Varanasi
Dr. Subhomoi Borkotoky (Postdoctoral Fellow funded by SERB project): completed 2020-22
Dr. Jay Prakash (CSIR Senior Research Associate): completed 2019-2022
Dr. Sunita Yadav (Postdoctoral Fellow; NPDF) 2018-2021
Mr. Umesh (SRF funded by CSIR project) 2020-21
Mr. Umesh Bhati (MTech student) completed 2020
Ms. Shalini Mishra (MTech student) completed 2021
Ms. Bhavya Ranjan (MTech student) completed 2021
Mr. Mihir Anand (final year IDD project) completed 2021
Mr. Pratap Digvijay (final year IDD project) completed 2021
Mr. Daniel Pegu (final year IDD project) completed 2021
Note: I am looking for self-motivated PhD candidates to join the group. Applicants for postdoctoral fellowship through external funding may also discuss about research interests .
Trained several postdocs, Research fellows, trainees etc
Lab Alumni at IIT Guwahati
Completed PhD/MTech students @ IIT Guwahati (17 PhD completed; 16 MTech completed)
S.No. |
Name |
Year of Completion |
Title of Thesis |
|
List of PhD students (21 completed) |
||||
List of PhD from IIT (BHU) Varanasi | ||||
21 | Dr. Preeti Ranjan | 2024 |
Studies on key enzyme(s) of leishmania parasite * Prime minister Fellowship |
|
20. |
Dr. Kumari Prerna Placement after PhD : University of Pennsylvania, USA |
2023 |
Studies on Proteins Involved in Cell Death/Survival Pathways |
|
19. |
Dr. Debanjan Kunau Placement after PhD : Georgia Institute of Technology Atlanta, USA |
2022 | Studies on Protein Folding, Stability and Amyloid Formation/Dissociation: Effect of Selected Biomolecules | |
18 |
Dr. Rahul Kumar Placement after PhD : Assistant Professor, Government of Bihar, India |
2022 | Natural and Synthetic based Polymeric Nanoparticles for Drug Delivery | |
List of PhD from IIT Guwahati | ||||
17 | Dr. Gundappa Saha* Placement after PhD: University of Pennsylvania, USA |
2020 | Deciphering novel immuno-suppressive mechanisms adopted by Leishmania donovani parasites in the pathogenesis of kala-azar * Prime minister Fellowship |
|
16 | Dr. Adarsh Kumar Chiranjivi Placement after PhD: Research Associate, Translational Health Science And Technology Institute, Faridabad |
2019 | Studies on dihydrolipoamide dehydrogenase of Leishmania donovani and its biochemical function | |
15 | Dr. Kamalesh Verma Placement after PhD : Research Associate, Translational Health Science And Technology Institute, Faridabad |
2020 | Studies on stable azoreductase enzyme from Chromobacterium violaceum: possible application in industrial effluent dye degradation | |
14 | Dr.Shyalami Sarma Placement : Senior Scientist, Sardar Patel Renewable Energy Research Institute, Gujarat |
2018 | Biohydrogen production from Crude Glycerol: Process Optimization and Intensification | |
13 |
Dr.Kartikeya Tiwari Placement after PhD : Postdoctoral Fellow Indiana University School of Medicine , USA |
2017 |
Physiological relevance of pyrimidine and aspartate metabolism in L. donovani through inhibition and knockout studies |
|
12 |
Dr. Ritesh Kumar Placement after PhD : Post doctoral Fellow, Baylor Institute for Immunology Research, Baylor Research Institute, Dallas, Texas, USA. |
2017 |
Exploring role of Methionine aminopeptidase 2 and other non-caspase proteases in program cell death of L. donovani |
|
11 |
Dr. Ruchika Bhardwaj Placement after PhD : National postdoctoral fellow at JNCASR, Bangalore |
2016 |
Studies on identification and in vivo function of novel drug target enzymes of Leishmania donovani using biomolecular approaches |
|
10 |
Dr. Shalinis Singh |
2016 |
Studies on identification of novel drug targets and discovery of novel drug candidates by exploring Leishmania Biochemistry |
|
9 |
Dr. Mousumi Das |
2015 |
Studies on redox system of Leishmania donovani: Understanding drug resistance process and discovery of novel drug candidates. |
|
8 |
Dr.Rohitas Deshmukh |
2014 |
Investigation of Macrophage medicated homeostatsis during malaria |
|
7 |
Dr. P. Saravanan |
2014 |
Bioinformatics approach to understand and exploit the potential o Lipases |
|
6 |
Dr. S. Basak |
2014 |
Molecular phylogeny of zingiberoideae |
|
5 |
Dr. Sushant Singh |
2014 |
Studies on Superoxide Dismutase: An antioxidative protein from Cicer arietinum L. seedlings |
|
4 |
Dr. Prakash Saudagar |
2013 |
Insights into redox metabolism of Leishmania parasite: Studies on key enzymes for novel drug candidates. |
|
3 |
Dr. Abhay Narain Singh |
2013 |
Studies on Procerain-B, a Novel Cysteine Protease from Calotropis Procera |
|
2 |
Dr. Anil Kumar Shukla |
2012 |
Targeting Redox Metabolism of Leishmania Parasite for Potential Chemotherapy of Leishmaniasis. |
|
1 |
Dr. Nandini Sarkar |
2011 |
Studies on effect of small molecule compounds on protein folding misfolding and amyloidogenesis |
List of M.Tech students (Completed: 15) |
|||
|
Ms. Aamen Talukdar |
2018 |
Studies on Leishmania donovani theranostic |
|
Ms. Prachi Bhalla |
2017 |
Synthesis of new oxabicyclic derivatives and its evaluation as antileishmanial |
|
Ms. Sona Sharma |
2016 |
Development of Novel antileishmanial compounds |
|
Ms. Ekta Kumari |
2015 |
Integrated computational and Biochemical studies on Glutamine synthetase of Leishmania donovani |
|
Mr. Ashish Kumar Singh Placement after M.Tech : PhD student,Ludwig-Maximilians-Universitat (LMU) Munich,Germany |
2014 |
Studies on Glutamine Synthetase of Leishmania donovani |
|
Mr. Ankur Kumar |
2014 |
Studies on CAAX Prenyl protease I of Leishmania donovani |
|
Mr. Robin Sachdeva |
2013 |
Studies on identification of novel drug target of Leishmania donovani |
|
Mr. Preet Lal |
2013 |
|
|
Ms.Ruchika Bhardwaj |
2012 |
Synthesis of Chitosan reduced Gold nanoparticles associated doxorubicin for evaluation of anti-leishmanial activity |
|
Ms. Prity Yadav |
2012 |
Soluble expression of procerain B in E. |
|
Ms. Neha Sharma |
2011 |
Study on various potential modulators of Redox Metabolism of Leishmania parasite. |
|
Ms. Deblina Chakraborty |
2011 |
Studies on CAAX prenyl protease I of Leishmania donovani |
|
Mr. B. Praveen Kumar |
2010 |
Effect of heavy metals on plants |
|
Ms. Sumithra |
2010 |
|
|
Mr. B. Leela Krishna |
2010 |
Isolation and purification of urease from plant sources |
-Smart India Hackathon 2022 coordinated at IIT (BHU) Varanasi nodal centre. August 25-26, 2022
-Short-term course on "Computer Aided Drug Design and Protein Analysis: February 22-26, 2021 at IIT (BHU) Varanasi (IDAPT-Hub supported)
-Recent Advancements in Biochemical Engineering and Biotechnology (http://rabeb2019.iitbhu.ac.in/ ) March 15-16, 2019 at IIT (BHU) Varanasi
-Recent Developments in Medical Biotechnology and Structure-Based Drug Designing December 6th to 7th , 2015 (at IIT Guwahati)
-Conference on Bioinformatics and Computer Aided Drug Design [CBCADD 2015] December 7th, 2015 (at IIT Guwahati)
- Symposium cum Workshop on "Advances in Computational Biology and Computer Aided Drug Design" June 24th to 26th, 2015 (at IIT Guwahati)
-QIP SHORT-TERM COURSE on "Advances In Drug Discovery" ( 20th-24th July 2009) (at IIT Guwahati)
-National Conference on recent Advancements in Environmental Research, June 4-5, 2016 (at IIT Guwahati)
-Organized several events as member of organizing committee
THIS SECTION IS NOT UPDATED
1. Vikash Kumar Dubey, Understanding redox metabolism and host defence mechanism of Leishmani donovani for possible therapeutics. Invited Talk, Emerging Trends in Disease Model Systems, 25-27 March 2019, National Centre for Cell Sciences, Pune.
2. Gundappa Saha, Bakulesh M Khamar, Manish Kumar Vikash Kumar Dubey. Leishmani donovani targets host proteins to alter the regulation of pyroptosis for their survival. Emerging Trends in Disease Model Systems, 25-27 March 2019, National Centre for Cell Sciences, Pune (P-11). Selected among best posters presentations for Award
3. Gundappa Saha, Bakulesh M Khamar, Manish Kumar Vikash Kumar Dubey. Blimp-1 playing a role in the regulation of pyroptosis during Leishmani donovani infection. Recent Advancements in Biochemical Engineering and Biotechnology, 15-16 March 2019, IIT (BHU) Varanasi (AB-02). Poster and Oral presentation by Gundappa Saha. Best oral presentation among young investigators
4. Kamalesh Verma, Lal Mohan Kundu and Vikash Kumar Dubey. Studies on stable azoreductase enzyme from Chromobacterium violaceum: application in industrial effluent dye degradation. Recent Advancements in Biochemical Engineering and Biotechnology, 15-16 March 2019, IIT (BHU) Varanasi (AB-05).
5. Adarsh Kumar Chiranjivi, Pranjal Chandra and Vikash Kumar Dubey. Site directed mutagenesis of Leishmani donovani Dihydrolipoamide dehydrogenase to investigate role of Cysteine 38, Alanine 48, Aspartate 49 and Alanine 54 in regulation of catalytic activity. Recent Advancements in Biochemical Engineering and Biotechnology, 15-16 March 2019, IIT (BHU) Varanasi (AB-18).
NOT UPDATED........
78. Kartikeya Tiwari and Vikash Kumar Dubey. Role of aspartate metabolism in the growth and infectivity of Leishmania donovani. 3rd International Conference on perspective of cell signaling and molecular medicine, 08-10 Jan 2016 at Bose Institute, Kolkata.
77. Kartikeya Tiwari and Vikash Kumar Dubey. Unraveling the role of L-asparaginase in the growth and infectivity of Leishmania donovani. 57 th Annual conference of Association of Microbiologists of India & International Symposium on Microbes and Biosphere: What's New What's Next, 24 -27 Nov, 2016 at Gauhati University. Assam, India
76. Kartikeya Tiwari and Vikash Kumar Dubey . Investigating pyrimidine metabolism of Leishmania donovani through dihydroorotase mediated inhibition. 9 th TCS Annual event and Flow Cytometry workshop on “Flow Application on Basic, Applied and Clinical Biology” (FABACTCS 2016), 03- 05 Nov, 2016 at IIT Guwahati, Guwahati. Assam, India.
75. Kartikeya Tiwari and Vikash Kumar Dubey . Exploring Leishmania donovani dihydroorotase as an effective drug target for antileishmanial therapy. Recent Developments In Medical Biotechnology And Structure Based Drug Designing (RDMBSBDD), 06-07 Dec 2015 at IIT Guwahati. Assam, India.
74. Ritesh Kumar and Vikash Kumar Dubey. Mechanistic elucidation of apoptosis in Leishmania : the important role of noncaspase proteases. 9 th TCS Annual event and Flow Cytometry workshop on “Flow Application on Basic, Applied and Clinical Biology” (FABACTCS 2016), 03- 05 Nov, 2016 at IIT Guwahati, Guwahati. Assam, India.
73. Ritesh Kumar and Vikash Kumar Dubey. Effect of TNP-470 on the apoptotic processes of miltefosine treated Leishmania donovani . 57 th Annual conference of Association of Microbiologists of India & International Symposium on Microbes and Biosphere: What's New What's Next, 24-27 Nov, 2016 at Gauhati University, Guwahati. Assam, India.
72. Ritesh Kumar and Vikash Kumar Dubey. Understanding the role of methionine aminopeptidase 2 in programmed cell death of Leishmania donovani by studying the knockout mutants. 3 rd International Conference on perspective of cell signaling and molecular medicine, 08-10 Jan 2016 at Bose Institute, Kolkata.
71. Prachi Bhalla, Anil Kumar Saikia and Vikash Kumar Dubey. Synthesis of second generation of Antileishmanial drugs. 9 th TCS Annual event and Flow Cytometry workshop on “Flow Application on Basic, Applied and Clinical Biology” (FABACTCS 2016), 03- 05 Nov, 2016 at IIT Guwahati, Guwahati. Assam, India.
70. Gundappa Saha, Bakulesh M Khamar and Vikash Kumar Dubey. Role of host Caspase 1 in the progression of Leishmania donovani infinfection. Cell Biology of Infection, October 13-14, 2016 at National Centre for Biological Sciences, TIFR, Bangalore, India.
69. Vikash Kumar Dubey. Recent development in Leishmania research: Promising drug candidates in pipeline. 8 th National symposia cum workshop on Recent Trends in Structural Bioinformatics and Computer Aided Drug Design 2016, February 16-19, 2016, Algappa University, Karaikudi[Invited talk].
68. Vikash Kumar Dubey. Admiring spermidine for its assorted functions: An integrated computational and Biochemical studies.. 7 th National symposia cum workshop on Recent Trends in Structural Bioinformatics and Computer Aided Drug Design 2015, February 24-27, 2015, Algappa University, Karaikudi[Invited talk].
67. Ruchika Bharadwaj and Vikash Kumar Dubey. “Investigating the role of a conserved hypothetical protein of Leishmania donovani “. 83 rd Annual Meeting of Society of Biological Chemists (SBCI), 17-21 December 2014, KIIT, Bhubaneswar.
66. Shalini Singh, Mousumi Das, Ruchika Bhardwaj and Vikash Kumar Dubey. Is Spermidine Synthase only a redox enzyme in Leishmania donovani ? 83 rd Annual Meeting of Society of Biological Chemists (SBCI), 17-21 December 2014, IIT, Bhubaneswar.
65. Sushant Singh, Anil Verma and Vikash Kumar Dubey . Oxidative Stress Environment Superoxide Dismutase; A Novel Antioxidative Protein Alleviating The Oxidative Stress Environment. Sustainable Development of Environmental Systems. IIT Guwahati, June 20-21, 2014
64 Ritesh Kumar and Vikash Kumar Dubey. Exploring the world of proteases in search of caspase like activity in Leishmania donovani. International Conference on "Future Prospects of Advancements in Biological Sciences, Health Issues & Environmental Protection, 07 - 08 Feb, 2014 at Indira Gandhi Pratishthan, Lucknow . [ Best poster presentation Award].
63 Ankur Kumar, Shalini Singh, Mousumi Das, Vikash Kumar Dubey . Validation of CAAX prenyl protease as a novel drug target against leishmaniasis. International Conference on "Future Prospects of Advancements in Biological Sciences, Health Issues & Environmental Protection, 07 - 08 Feb, 2014 at Indira Gandhi Pratishthan, Lucknow .
62 Ashish Kumar Singh and Vikash Kumar Dubey. Glutamine Synthetase as a novel drug target against Leishmaniasis. International Conference on "Future Prospects of Advancements in Biological Sciences, Health Issues & Environmental Protection. 07 - 08 Feb, 2014 at Indira Gandhi Pratishthan, Lucknow .
60 Mousumi Das and Vikash Kumar Dubey. Exploring ornithine decarboxylase of Leishmania donovani for potential drug against leishmaniasis. International Conference on Health, Environment and Industrial Biotechnology BioSangam -2013. Allahabad, November 21 - 23, 2013. [Oral Presentation; Best oral presentation Award].
59. Shalini Singh, Mousumi Das, Ankur Kumar and Vikash Kumar Dubey. Over-expression, purification and characterization of CAAX prenyl protease I and CAAX prenyl protease II of Leishmania donovani . Indraprastha International Conference on Biotechnology (IICB-2013), October 22-25, 2013, New Delhi.
58. Shilpa N. Patere, Pankaj O. Pathak 1 , Mangal S Nagarsenke , Anil Kumar Shukla , Rajesh Kumar Singh Vikash Kumar Dubey and Dibyendu Bhattacharya. Surface modified liposomal formulation of Amphotericin B for treatment of visceral leishmaniasis . 6 th International Conference organized by SAC- ACCP on Innovations in 21 st century: Clinical Pharmacology in current and future environment, on 21 - 22 April 2013, Mumbai (India)
57. Vikash Kumar Dubey. Betraying the redox system for leishmania parasite. International Meeting on Emerging Diseases and Surveillance (IMED 2013). Vienna, Austria. February 15–18, 2013.
56. Prakash Saudagar and Vikash K. Dubey*. Oxabicyclo derivatives as a new class of antileishmanial agents:target identification and understanding molecular mechanism of parasite death. International Meeting on Emerging Diseases and Surveillance (IMED 2013). Vienna, Austria. February 15–18, 2013. [DST Travel Award].
55. Vikash Kumar Dubey. Discovery of novel anti-leishmanial compounds by targeting redox metabolism of the parasite: Integrated computational and Biochemicalapproaches. Workshop on “Basics of Molecular Modelling and Computer-Aided Drug Designing”. College of Veterinary Science, Assam Agricultural University, Guwahati, January 8-10, 2013 [Invited as resource person and delivered a lecture].
54. Vikash Kumar Dubey and Nandini Sarkar. Exploring possibility of promiscuity of amyloid inhibitors. International Interdisciplinary Science Conference 2012 on protein folding and Diseases. Jamia Milia Islamia University, New Delhi, December 8-10, 2012.
53. Sushant Singh and Vikash Kumar Dubey*. Biomarkers: effect of pollutants on biological systems. Quality improvement programme (QIP) on “Green Chemistry and Clean Technology”. Organized by the Centre for Environment, IIT Guwahati. Guwahati, November 26-28, 2012. [Oral presentation].
52. Vikash Kumar Dubey. The complexity in Biology derives from simple Biochemistry. 9th BRSI Convention & International Conference on Industrial Biotechnology, Punjabi University, Patiala, November 21-23, 2012 [Malviya Memorial Award (Young Faculty) lecture]. [Invited talk].
51. Sushant Singh, Abhay Narayan Singh, Anil Verma and Vikash Kumar Dubey*. Nanoencapsulating superoxide dismutase/catalase towards enhancing antioxidative defense against generated oxidative stress. 81st Annual Meeting of the Society of Biological Chemists (India) & Symposium on Chemistry and Biology: Two Weapons against Diseases. Science city, Kolkata. November 8-11, 2012.
50. Abhay Narayan Singh and Vikash Kumar Dubey*. Procerain B; an industrially important cysteine protease. 81st Annual Meeting of the Society of Biological Chemists (India) & Symposium on Chemistry and Biology: Two Weapons against Diseases. Science city, Kolkata. November 8-11, 2012.
49. Anil Kumar Shukla, Sanjukta Patra and Vikash Kumar Dubey*. Redox metabolism of Leishmania parasite: Ideal target for drug development against leishmaniasis, 15th International Congress on Infectious Diseases, Bangkok, Thailand, June 13-16, 2012 [Abstract No. 21.002. [Oral presentation].
48. Sushant Singh, Abhay Narayan Singh, Anil Verma and Vikash Kumar Dubey*. Response to metal stress in plant: Superoxide dismutase, its purification and characterization from Cicer arietinum L.seedlings. One day symposium on “Environment and Us”. IIT Guwahati, Guwahati. June 05, 2012.
47. Vikash Kumar Dubey. Fun with Flagellated parasite. Second National Conference on Biotechnology, Bioinformatics and Bioengineering. Kolhapur, Maharashtra, February 24-25, 2012. [Invited talk].
46. Vikash Kumar Dubey. Computer added drug designing: targeting redox metabolism of Leishmania parasite. Workshop on "Bioinformatics: Application in Agriculture and Medical Sciences. Banaras Hindu University, Varanasi. Feb. 16-18, 2012. [Invited talk].
45. Vikash Kumar Dubey. Application of Bioinformatics in Protein Sciences. Workshop on "Bioinformatics: Application in Agriculture and Medical Sciences. Banaras Hindu University, Varanasi. Feb. 16-18, 2012. [Invited talk].
44. Anil Kumar Shukla, Sanjukta Patra and Vikash Kumar Dubey*. Targeting redox system of Leishmania parasite for drug discovery.18th International Conference of ISCB-2012 at IASST, Guwahati, India, Jan. 28-30, 2012.
43. Manjeet Kumar and Vikash Kumar Dubey*. Quinacrine a potential biomarker to trace amyloid plaque: studies on A 40 peptide and hen egg white lysozyme amyloid as model system. Annual Meeting of Indian Biophysical Society, held at University of Madras, Chennai, India. January 19-21, 2012.
42. Saravanan P, Vikash Kumar Dubey and Sanjukta Patra. Potential inhibitors targeting LdLip3 to combat Leishmaniasis. Annual Meeting of the Indian Biophysical Society organized by University of Madras, Chennai, India. January 19-21, 2012.
41. Saudagar Prakash and Vikash Kumar Dubey*. Trypanothion synthetase: A validated drug target enzyme from Leishmania donovani. The 18th International Conference (POST ISCBC-2012) IASST Guwahati, Assam, India. January 28-30, 2012.
40. Abhay Narayan Singh and Vikash Kumar Dubey*. Procerain B: an industrially important cysteine protease; Purification, characterization and cloning. The 18th International Conference (POST ISCBC-2012) IASST Guwahati, Assam, India. January 28-30, 2012.
39. Saravanan P, Aviansh H, Vikash Kumar Dubey and Sanjukta Patra. Targeting essential cell wall lipase rv3802c to combat tuberculosis: homology modeling, virtual screening and comparative docking studies. Open Source Computer-Aided for Translational Medicine organized by IMTECH, Chandigarh, India. Febuary 22-25, 2012. [Oral presentation].
38. Vikash Kumar Dubey, Anil Kuamr Shukla and Prakash Saudagar Dubey. Current trends in anti-leishmanial drug discovery. International conference on New Horizones in Biotechnology, Trivandrum, India, November 21-24, 2011. [Invited talk].
37. Prakash Saudagar and Vikash Kumar Dubey*. Trypanothione Synthetase from L. donovani : Cloning, expression, characterization, and inhibition studies. 80th Annual Meeting of Society of Biological Chemists, held at Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India, November 12-15, 2011. [Best poster Award].
36. Prity Yadav, Abhay Narayan Singh and Vikash Kumar Dubey*. Heterologous expression of a novel plant cysteine protease: procerain B in E. coli and site directed mutagenesis to study the amino acids at catalytic triad. 80th Annual Meeting of Society of Biological Chemists, held at Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India, November 21-24, 2011. [Oral presentation].
35. Mousumi Das and Vikash Kumar Dubey*. Exploring ornithine decarboxylase for novel drugs against Leishmania donovani. 80th Annual Meeting of Society of Biological Chemists, held at Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India, November 12-15, 2011.
34. Manjeet Kumar and Vikash Kumar Dubey*. Quinacrine: as potential antemortem diagnostic dye for Alzheimer's disease. 80th Annual Meeting of Society of Biological Chemists, held at Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India, November 12-15, 2011.
33. Ruchika Bhardwaj, Anil Kumar Shukla and Vikash Kumar Dubey*. Synthesis of Chitosan-PEG coated Gold nanoparticles entrapping doxorubicin for evaluation of anti-leishmanial activity and targeted delivery to macrophage. 80th Annual Meeting of Society of Biological Chemists, held at Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India, November 12-15, 2011.
32. Shyamali Sarma and Vikash Kumar Dubey*. Cloning, expression and characterization of spermidine synthase, a drug target enzyme of Leishmania donovani. 80th Annual Meeting of Society of Biological Chemists, held at Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India, November 12-15, 2011.
31. Sushant Singh, Abhay Narayan Singh, Anil Verma, Vikash Kumar Dubey*. Heavy metal stress induced Superoxide dismutase: Purification and characterization from Cicer arietinum L. seedlings. 80th Annual Meeting of Society of Biological Chemists, held at Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India, November 12-15, 2011.
30. Abhay Narayan Singh and Vikash Kumar Dubey*. Physiochemical characterization, immobilization and cloning of procerain B: an industrially important plant cysteine protease. 80th Annual Meeting of Society of Biological Chemists, held at Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India, November 12-15, 2011.
29. Anil Kumar Shukla and Vikash Kumar Dubey. Synthesis of PEGylated nanospheres encapsulating doxorubicin and mitomycin C for their specific macrophage targeting, reduced toxicity and enhanced antileishmanial activity. 3rd EMBO meeting, Vienne, September 10-13, 2011. [DBT Travel Award].
28. Sushant Singh, Anil Verma and Vikash Kumar Dubey*. Effects of increasing Aluminium metal stress in germinating chickpea (Cicer arietinum) seeds. International Conference on Climate Change and Water: Assessing vulnerability, impact, and adaptation in the Eastern Himalayas. IIT Guwahati, Assam, January 3-5, 2011.
27. Abhay Narayan Singh and Vikash Kumar Dubey*. Procerain B a potential candidate for protease industry. World Congress on Biotechnology, Hyderabad, India, March 21-23, 2011.
26. Neha Sharma, Anil Kumar Shukla and Vikash Kumar Dubey*. Evaluation of Plumbagin and its derivative as potential modulator of Redox Thiol Metabolism of Leishmania parasite. World Congress on Biotechnology, Hyderabad, India, March 21-23, 2011.
25. Vikash Kumar Dubey, Subversive substrate of Trypanothione Reductase: a key for anti-leishmanial drug discovery. International conference on Genomics Science-Recent Trend (ICGS-2010). Madurai Kamraj University, Madurai, Nov. 12-14, 2010. [Special Invited talk as recipient of Young Scientist Award of Biotech Research Society].[Invited talk].
24. Vikash Kumar Dubey. Potential therapeutics against Leishmaniasis: Deciphering the molecular mechanism underlying the activity of antitumor agents as antileishmanial and their potential for therapy. National Conference on Biological Chemistry (NCBC-2010), Gitam Universuty, Visakhapatnam, November 29-30, 2010. [Invited talk].
23. S. Basak, Tushar, A. Das, V.K. Dubey and L. Rangan. Phylogenic analysis of Zingiberaceae native to Northeast India using RAPIS marker. International conference on Genomics Science-Recent Trend (ICGS-2010). Madurai Kamraj University, Madurai, Nov. 12-14, 2010.
22. Anil Kumar Shukla and Vikash Kumar Dubey*. Biophysical properties of TryR from Leishmania infantum: a step towards drug development for Leishmaniasis. International Conference on Frontiers on Biological Sciences. NIT, Rourkela. October 1-3, 2010.
21. Prakash Saudagar, Santhosh Kannan Venkatesan and Vikash Kumar Dubey* Molecular modeling, virtual screening and comparative analysis of. Trypanothione Synthetase from L. donovani and L. major for the identification of new inhibitors as a drug. International Conference on Frontiers on Biological Sciences. NIT, Rourkela. October 1-3, 2010. [Oral presentation].
20. Sushant Singh, Anil Verma and Vikash Kumar Dubey*. Oxidative stress analysis in germinated Chickpea seeds under copper ions. International Conference on Frontiers on Biological Sciences (INCOFIBS). NIT, Rourkela. October 1-3, 2010. [Oral presentation].
19. Anil Kumar Shukla and Vikash Kumar Dubey*. Molecular Mechanism underlying the Anti-leishmanial activity of Nyctanthes arbortristis. 4th International conference on 'Current trends in drug discovery research (CTDDR-2010). Central Drug Research Institute, Lucknow. February 17-21, 2010.
18. Nandini Sarkar and Vikash K. Dubey*. Effect of small molecule aggregators on amyloid formation of proteins. Symposium on Recent Trends in Biophysics. Organized Indian Biophysical Society, Banaras Hindu University, Varanasi, February 13-15, 2010.
17. Anil Kumar Shukla, Santhosh Kannan V. and Vikash Kumar Dubey*. Studies on Trypanothione Reductase from Leishmania infantum. 78th Annual Meeting of Society of Biological Chemists, India held at National Centre for Cell Science and University of Pune, Oct. 30-Nov. 1, 2009.
16. Santhosh Kannan V, Anil Kumar Shukla and Vikash Kumar Dubey*. Structure based virtual screening approach to identify potential inhibitors of Trypanothione reductase from Leishmania infantum. 78th Annual Meeting of Society of Biological Chemists, India held at National Centre for Cell Science and University of Pune, Oct. 30-Nov. 1, 2009.
15. Abhay Narain Singh, and Vikash Kumar Dubey*. Procerain B a novel cysteine protease from the latex of medicinal plant Calotropis procera. 78th Annual Meeting of Society of Biological Chemists, India held at National Centre for Cell Science and University of Pune, Oct. 30-Nov. 1, 2009.
14. Nandini Sarkar, Abhay Narain Singh, Vikash K. Dubey*. Identification of amyloidogenic folding intermediate state of 2,5-Diketo-D-Gluconate Reductase A: Effect of Curcumin on Amyloid formation.21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology held on 2-7 August 2009 and Young Scientist Program held on July30-August 2, 2009 in Shanghai, China. [The work was selected for IUBMB full travel fellowship funding and Young Scientist Program Award].
13. Abhay Narain Singh, Bishal Kumar Singh, and Vikash Kumar Dubey*. Drug designing against leishmaniasis by targeting parasite specific trypanothione metabolic pathway. NE Conference of Medical Microbiologysts-09. Guwahati Medical College Guwahati, April 24-26, 2009.
12. Nandini Sarkar, and Vikash Kumar Dubey*. Studies on 2,5 Diketo D Gluconate Reductase: Identification of Amyloid forming folding intermediate under acidic condition. 77th Annual Meeting of Society of Biological Chemists, India held at IIT Madras, Chennai December 18-20, 2008. [Received B.S Narasinga Rao Best Poster presentation Award].
11. Bishal Kumar Singh, and Vikash Kumar Dubey*. Structure of Trypanothione Reductase of Leishmania infantum: A therapeutic target for drug discovery. International conference on Biotechnology, Vellore Institute of Technology, India. February 6-8, 2008.
10. Jihun Lee, Vikash Dubey, L. Longo and Michael Blaber A Logical OR Redundancy within the Asx-Pro-Asx-Gly Type I b-turn Motif. 22nd Annual Symposium of The Protein Society. July 19-23, 2008 at the San Diego, California, USA. [Published in Protein Science, Vol 17, Suppl. 1, p232, 2008].
9. Vikash Kumar Dubey, Jihun Lee, Thayumanasamy Somasundaram and Michael Blaber. Stability, folding and functional consequences of imposed primary structure symmetry of FGF-1. Research Fair, College of Medicine, Florida State University, Tallahassee, USA, Feb., 28, 2006.
8. Jihun Lee, Vikash Kumar Dubey, and Michael Blaber. Effect of type I 3:5 G1 bulge ?-turn on protein stability and folding kinetics. Research Fair, College of Medicine, Florida State University, Tallahassee, USA, Feb., 28, 2006.
7. Vikash Kumar Dubey and Michael Blaber. Redesigning symmetry-related mini-core regions of FGF-1 to increase primary structure symmetry. 19th Annual Symposium of Protein Society. Boston, USA. July 29 - Aug. 3, 2005. [Published in Protein Science, Vol 14, Suppl. 1, p75, 2005].
6. Vikash K. Dubey, Stephen R. Brych, Jihun Lee, and Michael Blaber. Protein symmetry, stability and function, CALCON 2004 - the 59th Annual Calorimetry Conference, Santa Fe, New Mexico, USA, June 27 - July 1, 2004.
5. Carlo Travaglini-Allocatelli, Stefano Gianni, M.G. Bigotti Alessandro Borgia, Vikash K. Dubey, Francesca Cutruzzola and Maurizio Brunori. The folding landscape of cytochrome c family: tarps, intermediate and pathways. European Molecular Biology Organizations meeting on Protein folding and misfolding. Rome, Italy, April 3-5, 2003.
4. Vikash Kumar Dubey and M.V. Jagannadham. Equilibrium Unfolding of procerain: Sequential unfolding in molten globule like state. European Molecular Biology Organizations meeting on Protein folding and misfolding. Rome, Italy, April 3-5, 2003.
3. Vikash Kumar Dubey and M.V. Jagannadham. Procerain, a stable cysteine protease from Calotropis procera. International Symposium on Stabilization of Enzyme and Biosensors, Chennai, India. November 24-29, 2001.
2. Attended research scholars conference on Frontier areas of science, engineering and technology (VISION-2001) at Department of physics, Banaras Hindu University, Varanasi, India, May 6, 2001.
1. Vikash Kumar Dubey and M.V. Jagannadham. Cleavage of one specific disulfide bond of Ervatamin C. National Symposium on Biophysics, at Institute of Chemical Biology, Calcutta, India, January 15-17, 2001.